Tom Hobman received his Ph.D. degree from the University of British Columbia, Vancouver, BC, Canada in 1990. After completing his postdoctoral studies at the University of California, San Diego, he accepted a faculty position at the Department of Cell Biology at the University of Alberta, Edmonton, Canada in 1994. Hobman is the holder of a Scientist Award from the Alberta Heritage Foundation for Medical Research and currently holds the rank of a Professor at the Departments of Cell Biology, Medical Microbiology, and Immunology. He has had a long-standing interest in the cell biology of RNA viruses. Specifically, the Hobman Laboratory is interested in the study of virus-host interactions that occur at the cellular level. Over the last 8 years, they have focused on nonstructural functions of RNA virus capsid proteins in their studies. The central hypothesis of these studies is that in addition to performing their functions as building blocks of new virions, viral capsid proteins interact with a multitude of host cell proteins to modify the host cell environment. These interactions may be important for virus replication and/or development of disease. In addition to virology, the Hobman Laboratory is interested in the biogenesis and functions of argonaute proteins. Argonaute proteins are the central effectors of RNA interference.
Biography Updated on 21 June 2009