S. Patricia Becerra0000-0002-0646-9729
Patricia Becerra serves as a Principal Investigator and the Head of the Section of Protein Structure and Function, Laboratory of Retinal cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, Md, USA. She received a Ph.D. degree (major in biochemistry) from the University of Navarra, Spain, in 1979. Her postdoctoral training was in biochemistry of DNA polymerases at the National Cancer Institute, Bethesda, Md, USA, and in molecular virology of AAV at the National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md. The interests of her laboratory are in the area of protein structure as it relates to function, with a focus on the interactions of components involved in cell differentiation, survival, and maintenance. The research of her laboratory at NEI has applied these interests to systems in the retina. In particular, her laboratory has worked on PEDF, an important multifunctional serpin for the eye and a potential therapeutic agent for neural- and vascular-related diseases. Among her major accomplishments are the following: identification of the first eukaryotic non-AUG initiation codon for translation and structure-function relationships of PEDF. She serves as an editorial board member and reviewer of several journals in biochemistry, molecular biology, and ophthalmology. Her research interests are structure-function relationships of proteins with current emphasis in the biochemistry and molecular biology of proteins affecting the retina.
Biography Updated on 15 February 2012