Dr Shyam Sundar is a Professor of Medicine, and is working continuously on the neglected disease kala-azar for two decades, and on HIV infection for last 10 years. He directs the Infectious Diseases Research laboratory, he is founder of the Kala-azar Medical Research Center. Due to a critical need for management of the fatal disease visceral leishmaniasis in poor populations of Bihar State, India, Dr Shyam Sundar established a modest field site (Kala-azar Medical Research Center) at Muzaffarpur, Bihar for treatment of visceral leishmaniasis. It has its own clinical laboratory with the capacity to measure hematological and biochemical parameters. There are in all five physicians who take care of the patients, and approximately 5000 outpatients are seen in the out door clinic every year. About 1000-1200 patients with VL are provided care each year. This institution is now considered a leading clinical facility for visceral leishmaniasis world-wide. A further development of Dr Sundar's work in Bihar State has been to take the study of visceral leishmaniasis into the village communities that surround Muzaffarpur in Bihar State. Dr Sundar has unambiguously been one of the major contributors to the advancement of current strategies for treating visceral leishmaniasis. Highlights of his accomplishments include the following. • He was first to document large scale failure of the mainstay of therapy (antimony or Sb) in Bihar, and the emergence of Sb refractory leishmania parasites in Bihar state. He investigated the problem of antimony resistance amongst Indian L donovani isolates and documented novel mechanisms of drug resistance.
Biography Updated on 15 January 2011