Jose Luis Gonzalez De Aguilar

Jose Luis Gonzalez De Aguilar serves as Associate Professor of animal physiology at the University of Strasbourg, Alsace, France. He received the INSERM Chair of Excellence in neuroscience. Aguilar started his career by studying regulatory aspects of the amphibian hypothalamo-pituitary axis in response to environmental changes. In 1996, he obtained his Ph.D. degree in biological sciences from the University of Córdoba (Spain). Afterwards, he joined the Institute of Cellular Physiology and Biochemistry in the University of Strasbourg, Alsace, France, to work in the field of neurodegenerative diseases. Since then, his studies has been dealing with the understanding of amyotrophic lateral sclerosis, which is a fatal disease of the motor system, frequently associated with other degenerative processes such as frontotemporal lobar degeneration. In collaboration with the Center of Neurochemistry of Strasbourg, Aguilar's initial investigations concentrated on the development of synthetic neurotrophic substances with neuroprotective properties. Since 2005, he has been affiliated with the INSERM Laboratory of Molecular Signaling and Neurodegeneration in Strasbourg and focuses his work on the analysis of the relationships between motor neuron disease and dysfunction of lipid metabolism. By applying global profiling approaches, including transcriptomics and metabolomics to both patients and related animal models of disease, Aguilar is currently in charge of a research program devoted to the identification of molecular markers of clinical relevance that also shed light on the underlying mechanisms of motor neuron disease.

Biography Updated on 4 May 2012

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