Luciano D'Adamio received his M.D. degree from the University of Perugia (Italy) in 1985 and his Ph.D. degree from the University of Rome (Italy) in 1991. From 1988 to 1992, he worked at the Dana Farber cancer Institute at the Harvard Medical School investigating the mechanisms of immune tolerance in the thymus, working with Dr. Ellis Reinherz. After a brief period as a Visiting Professor at the University of Perugia, he became Tenure Track Principal Investigator at the National Institute of Allergy and Infectious Diseases in Bethesda (Md, USA). Here he developed a functional screening system to identify genes involved in T cells apoptosis. After spending three months on a sabbatical at the Basel Institute for Immunology, Dr. D'Adamio joined the Albert Einstein College of Medicine as an Irene Diamond Associate Professor of immunology in 2000. In 2004, he became a Full Professor. While at NIH and AECOM, he became interested in the molecular mechanisms of neurodegeneration and Alzheimer's disease pathogenesis. During the last ten years, he has investigated the role of APP processing in neuronal cell death and the molecular mechanisms regulating APP processing. These studies have suggested new links between genetic forms of dementia, such as Familial Alzheimer's, British, and Danish dementias. His studies are of a general relevance to the field of Alzheimer's disease both for understanding the etiopathogenesis of the disease and for developing therapies aiming to improve this devastating pathology.
Biography Updated on 17 October 2011