David R. Brown
David R. Brown was born in Sydney, Australia, but currently works in the Department of Biology and Biochemistry at the University of Bath in England. Professor Brown’s main interest is the basic mechanisms behind neurodegenerative disorders. In particular, he has shown that metals bind to a variety of proteins, including the prion protein. His current work has focussed on metal binding to a-synculein. He serves as an editor for the Journal of Neurochemistry and is currently a Member of the prestigious SEAC committee (Spongiform Encephalopathy Advisory Committee), advising the UK government on issues related to bovine spongiform encephalopathy and Creutzfeldt–Jakob disease.
Biography Updated on 13 August 2007
Articles in Scholarly Journals [Incomplete List]
- Anterograde axonal transport of chicken cellular prion protein (PrPc) in vivo requires its N-terminal part
Journal of Neuroscience Research, vol. 85, no. 12, pp. 2567–2579, 2007 - Real-time kinetics of discontinuous and highly conformational metal-ion binding sites of prion protein
JBIC Journal of Biological Inorganic Chemistry, vol. 12, no. 5, pp. 711–720, 2007 - Dual polarisation interferometry analysis of copper binding to the prion protein: Evidence for two folding states
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, vol. 1774, no. 7, pp. 920–927, 2007 - Prion protein does not redox-silence Cu2+, but is a sacrificial quencher of hydroxyl radicals
Free Radical Biology and Medicine, vol. 42, no. 1, pp. 79–89, 2007 - The healthy brain and our aging population: Translating science to public health practice
Alzheimer's and Dementia, vol. 3, no. 2, pp. S3–S5, 2007 - Regulation of Prion Protein Expression by Noncoding Regions of the Prnp Gene
Journal of Molecular Biology, vol. 368, no. 4, pp. 915–927, 2007 - Autonomic neurotransmitters modulate immunoglobulin A secretion in porcine colonic mucosa
Journal of Neuroimmunology, vol. 185, no. 1-2, pp. 20–28, 2007 - Anatomical evidence for enteric neuroimmune interactions in Peyer’s patches
Journal of Neuroimmunology, vol. 185, no. 1-2, pp. 64–74, 2007 - Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine
Veterinary Microbiology, vol. 120, no. 3-4, pp. 328–333, 2007 - NMR characterization of the pH 4 ß-intermediate of the prion protein: the N-terminal half of the protein remains unstructured and retains a high degree of flexibility
Biochemical Journal, vol. 401, no. 2, p. 533, 2007 -
An Assessment of Risk from Particulate Released from Outdoor Wood Boilers
Human and Ecological Risk Assessment, vol. 13, no. 1, pp. 191–208, 2007 - Response to Christopher M. Long and Peter Valberg (2007) "Comments on Brown et al. (2007) An Assessment of Risk from Particulate Released from Outdoor Wood Boilers." Hum. Ecol. Risk Assess. 13(1)
Human and Ecological Risk Assessment, vol. 13, no. 3, pp. 686–690, 2007 - Ancient conserved domain protein-1 binds copper and modifies its retention in cells
Journal of Neurochemistry, vol. 0, no. 0, pp. 070702072507004–???, 2007 - Introduction: Copper and amyloid fibril formation
FEBS Journal, vol. 274, no. 15, pp. 3755–3755, 2007 - Interactions between metals and ?-synuclein???function or artefact?
FEBS Journal, vol. 274, no. 15, pp. 3766–3774, 2007 - Modelling neurodegeneration in prion disease ? applications for drug development
Expert Opinion on Drug Discovery, vol. 2, no. 6, pp. 777–788, 2007 - WHAT IS A WINTER FLOATER? CAUSES, CONSEQUENCES, AND IMPLICATIONS FOR HABITAT SELECTION
The Condor, vol. 109, no. 3, p. 548, 2007 - Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie and bovine spongiform encephalopathy
Journal of Animal Science, vol. 85, no. 6, pp. 1596–1609, 2007 - Genetic Manipulation of Intraspinal Plasticity after Spinal Cord Injury Alters the Severity of Autonomic Dysreflexia
Journal of Neuroscience, vol. 26, no. 11, pp. 2923–2932, 2006 - Mouse galectin-1 inhibits the toxicity of glutamate by modifying NR1 NMDA receptor expression
European Journal of Neuroscience, vol. 24, no. 11, pp. 3017–3025, 2006 - Prion protein reduces both oxidative and non-oxidative copper toxicity
Journal of Neurochemistry, vol. 98, no. 3, pp. 677–689, 2006 - Copper-dependent co-internalization of the prion protein and glypican-1
Journal of Neurochemistry, vol. 98, no. 5, pp. 1445–1457, 2006 - Empirical and theoretical analysis of the extremely low frequency arterial blood pressure power spectrum in unanesthetized rat
AJP: Heart and Circulatory Physiology, vol. 291, no. 6, pp. H2816–H2824, 2006 - Synthesis and Characterization of Luminescent Yttrium Oxide Doped with Tm and Yb
Journal of the American Ceramic Society, vol. 89, no. 3, pp. 926–931, 2006 - Experimental fruit removal does not affect territory structure of wintering Hermit Thrushes
Journal of Field Ornithology, vol. 77, no. 4, pp. 404–408, 2006 - High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation
FEBS Journal, vol. 273, no. 18, pp. 4250–4263, 2006 - Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system
Molecular and Cellular Neuroscience, vol. 31, no. 1, pp. 97–108, 2006 - serovar Choleraesuis infection of the porcine jejunal Peyer's patch rapidly induces IL-1ß and IL-8 expression
Veterinary Immunology and Immunopathology, vol. 109, no. 1-2, pp. 1–11, 2006 - Differential effects of clathrin and actin inhibitors on internalization of Escherichia coli and Salmonella choleraesuis in porcine jejunal Peyer's patches
Veterinary Microbiology, vol. 113, no. 1-2, pp. 117–122, 2006 - Mucosally-directed adrenergic nerves and sympathomimetic drugs enhance non-intimate adherence of Escherichia coli O157:H7 to porcine cecum and colon
European Journal of Pharmacology, vol. 539, no. 1-2, pp. 116–124, 2006 - Hydrogen peroxide cleavage of the prion protein generates a fragment able to initiate polymerisation of full length prion protein
The International Journal of Biochemistry & Cell Biology, vol. 38, no. 8, pp. 1429–1440, 2006 - Food supply controls the body condition of a migrant bird wintering in the tropics
Oecologia, vol. 149, no. 1, pp. 22–32, 2006 - Copper binding is the governing determinant of prion protein turnover
Molecular and Cellular Neuroscience, vol. 30, no. 2, pp. 186–196, 2005 - Mucosal vaccination delays or prevents prion infection via an oral route
Neuroscience, vol. 133, no. 2, pp. 413–421, 2005 - Mediation of neurogenic ion transport by acetylcholine, prostanoids and 5-hydroxytryptamine in porcine ileum
European Journal of Pharmacology, vol. 519, no. 3, pp. 285–289, 2005 - Probing Copper2+ Binding to the Prion Protein Using Diamagnetic Nickel2+ and 1H NMR: The Unstructured N terminus Facilitates the Coordination of Six Copper2+ Ions at Physiological Concentrations
Journal of Molecular Biology, vol. 346, no. 5, pp. 1393–1407, 2005 - High Affinity Binding between Copper and Full-length Prion Protein Identified by Two Different Techniques
Journal of Biological Chemistry, vol. 280, no. 52, pp. 42750–42758, 2005 - Adrenocorticotrophic hormone modulates Escherichia coli O157:H7 adherence to porcine colonic mucosa
Stress: The International Journal on the Biology of Stress, vol. 8, no. 3, pp. 185–190, 2005 - Consequences, Ethical Obligations, IRIS, NAS Reviews and Perchlorate in Drinking Water
Human and Ecological Risk Assessment, vol. 11, no. 3, pp. 477–482, 2005 - Differential acquisition of specific components of a classically conditioned arterial blood pressure response in rat
AJP: Regulatory, Integrative and Comparative Physiology, vol. 289, no. 3, pp. R784–R788, 2005 - An Aggregation-Specific Enzyme-Linked Immunosorbent Assay: Detection of Conformational Differences between Recombinant PrP Protein Dimers and PrPSc Aggregates
Journal of Virology, vol. 79, no. 19, pp. 12355–12364, 2005 - AT1-receptor antagonism reverses the blood pressure elevation associated with diet-induced obesity
AJP: Regulatory, Integrative and Comparative Physiology, vol. 289, no. 1, pp. R181–R186, 2005 - Physical Activity among Adults ???50 yr with and without Disabilities, BRFSS 2001
Medicine & Science in Sports & Exercise, vol. 37, no. 4, pp. 620–629, 2005 - Behavioral Response of Resident Jamaican Birds to Dry Season Food Supplementation1
Biotropica, vol. 0, no. 0, p. 051128134355004, 2005 - Therapeutics and Prion Disease: Can Immunisation or Drugs be Effective?
Mini Reviews in Medicinal Chemistry, vol. 5, no. 4, pp. 361–366, 2005 - The use of peptides that pick up prions: protection or poison?
Expert Opinion on Therapeutic Patents, vol. 15, no. 9, pp. 1287–1290, 2005 - Frugivory by Wintering Hermit Thrush In Louisiana
Southeastern Naturalist, vol. 4, no. 4, p. 627, 2005 - Lessons from the porcine enteric nervous system
Neurogastroenterology and Motility, vol. 16, no. s1, pp. 50–54, 2004 - Associations between Physical Activity Dose and Health-Related Quality of Life
Medicine & Science in Sports & Exercise, pp. 890–896, 2004 - Adrenergic modulation of Escherichia coli O157:H7 adherence to the colonic mucosa
AJP: Gastrointestinal and Liver Physiology, vol. 287, no. 6, pp. G1238–G1246, 2004 - Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension
AJP: Regulatory, Integrative and Comparative Physiology, vol. 287, no. 4, pp. R943–R949, 2004 - Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors
NeuroReport, vol. 15, no. 3, pp. 483–486, 2004 - Journal of Medicinal Chemistry, vol. 47, no. 22, pp. 5515–5534, 2004
- Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases
Dalton Transactions, no. 13, p. 1907, 2004 - Role of the prion protein in copper turnover in astrocytes
Neurobiology of Disease, vol. 15, no. 3, pp. 534–543, 2004 - Astrocytic regulation of NMDA receptor subunit composition modulates the toxicity of prion peptide PrP106–126
Molecular and Cellular Neuroscience, vol. 25, no. 1, pp. 181–191, 2004 - Prion protein fate governed by metal binding
Biochemical and Biophysical Research Communications, vol. 325, no. 3, pp. 1005–1012, 2004 - BSE and vCJD cause disturbance to uric acid levels
Experimental Neurology, vol. 190, no. 1, pp. 233–244, 2004 - Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region
Journal of Inorganic Biochemistry, vol. 98, no. 1, pp. 133–143, 2004 - Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice
The Journal of Pathology, vol. 203, no. 1, pp. 603–608, 2004 - Physical Activity and Body Mass Index Among US Adolescents: Youth Risk Behavior Survey, 1999
Archives of Pediatrics and Adolescent Medicine, vol. 157, no. 8, pp. 816–820, 2003 - Characterization of specific d-opioid binding sites in the distal small intestine of swine
European Journal of Pharmacology, vol. 482, no. 1-3, pp. 111–116, 2003 - Conformational exposure: a new handle on prions
The Lancet, vol. 362, no. 9388, pp. 929–930, 2003 - Neuromodulation of enteropathogen internalization in Peyer's patches from porcine jejunum
Journal of Neuroimmunology, vol. 141, no. 1-2, pp. 74–82, 2003 - Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106–126
Neuroscience Letters, vol. 336, no. 3, pp. 159–162, 2003 - Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa
British Journal of Pharmacology, vol. 140, no. 4, Article ID 0705485, 9 pages, 2003 - Analysis of doppel protein toxicity
Molecular and Cellular Neuroscience, vol. 23, no. 1, pp. 144–155, 2003 - Biochemistry, vol. 42, no. 25, pp. 7675–7681, 2003
- Mapping the functional domain of the prion protein
European Journal of Biochemistry, vol. 270, no. 16, pp. 3368–3376, 2003 - A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation
European Journal of Neuroscience, vol. 18, no. 3, pp. 571–579, 2003 - Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein
Biochemical Journal, vol. 370, no. 1, p. 81, 2003 - Prion protein expression modulates neuronal copper content
Journal of Neurochemistry, vol. 87, no. 2, pp. 377–385, 2003 - Copper Chelation Delays the Onset of Prion Disease
Journal of Biological Chemistry, vol. 278, no. 47, pp. 46199–46202, 2003 - Catecholamines Modulate Escherichia coli O157:H7 Adherence to Murine Cecal Mucosa
Shock, vol. 20, no. 2, pp. 183–188, 2003 - Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126
NeuroReport, vol. 14, no. 13, pp. 1743–1745, 2003 - Kinin-Induced Anion-Dependent Secretion in Porcine Ileum: Characterization and Involvement of Opioid- and Cannabinoid-Sensitive Enteric Neural Circuits
Journal of Pharmacology and Experimental Therapeutics, vol. 305, no. 2, pp. 733–739, 2003 - Characterization of Specific Opioid Binding Sites in Neural Membranes from the Myenteric Plexus of Porcine Small Intestine
Journal of Pharmacology and Experimental Therapeutics, vol. 308, no. 1, pp. 385–393, 2003 - Predominance of delta -Opioid-Binding Sites in the Porcine Enteric Nervous System
Journal of Pharmacology and Experimental Therapeutics, vol. 300, no. 3, pp. 900–909, 2002 - Physical activity, sports participation, and suicidal behavior among college students
Medicine & Science in Sports & Exercise, vol. 34, no. 7, pp. 1087–1096, 2002 - Endocannabinoids as physiological regulators of colonic propulsion in mice
Gastroenterology, vol. 123, no. 1, pp. 227–234, 2002 - Mayhem of the multiple mechanisms: modelling neurodegeneration in prion disease
Journal of Neurochemistry, vol. 82, no. 2, pp. 209–215, 2002 - Biochemistry, vol. 41, no. 22, pp. 6891–6896, 2002
- Metal imbalance and compromised antioxidant function are early changes in prion disease
Biochemical Journal, vol. 362, no. 1, p. 253, 2002 - Gastric antisecretory role and immunohistochemical localization of cannabinoid receptors in the rat stomach
British Journal of Pharmacology, vol. 135, no. 7, Article ID 0704625, 8 pages, 2002 - Cannabinoids throw up a conundrum
British Journal of Pharmacology, vol. 137, no. 5, Article ID 0704913, 2 pages, 2002 - Active bicarbonate-dependent secretion evoked by 5-hydroxytryptamine in porcine ileal mucosa is mediated by opioid-sensitive enteric neurons
European Journal of Pharmacology, vol. 451, no. 2, pp. 185–190, 2002 - High Extracellular Potassium Protects against the Toxicity of Cytosine Arabinoside but Is Not Required for the Survival of Cerebellar Granule Cells in Vitro
Molecular and Cellular Neuroscience, vol. 19, no. 2, pp. 281–291, 2002 - Relationship of Satisfaction with Body Size and Trying to Lose Weight in a National Survey of Overweight and Obese Women Aged 40 and Older, United States
Preventive Medicine, vol. 35, no. 4, pp. 390–396, 2002 - Chemical coding of neurons expressing δ- and κ-opioid receptor and type I vanilloid receptor immunoreactivities in the porcine ileum
Cell and Tissue Research, vol. 307, no. 1, pp. 23–33, 2002 - Demographic Effects of Habitat Selection by Hermit Thrushes Wintering in a Pine Plantation Landscape
The Journal of Wildlife Management, vol. 66, no. 2, p. 407, 2002 - Copper-Dependent Functions for the Prion Protein
Molecular Biotechnology, vol. 22, no. 2, pp. 165–178, 2002 - Molecular Advances in Understanding Inherited Prion Diseases
Molecular Neurobiology, vol. 25, no. 3, pp. 287–302, 2002 - Microglia and prion disease
Microscopy Research and Technique, vol. 54, no. 2, pp. 71–80, 2001 - Lack of prion protein expression results in a neuronal phenotype sensitive to stress
Journal of Neuroscience Research, vol. 67, no. 2, pp. 211–224, 2001 - Desiccation Tolerance in Human Cells
Cryobiology, vol. 42, no. 3, pp. 207–217, 2001 - Induction of HO-1 and NOS in Doppel-Expressing Mice Devoid of PrP: Implications for Doppel Function
Molecular and Cellular Neuroscience, vol. 17, no. 4, pp. 768–775, 2001 - Air quality measures and public health policy
Public Health Reports, vol. 116, no. 1, pp. 61–63, 2001 - Opioid receptors on bone marrow neutrophils modulate chemotaxis and CD11b/CD18 expression
European Journal of Pharmacology, vol. 414, no. 2-3, pp. 289–294, 2001 - Copper and prion disease
Brain Research Bulletin, vol. 55, no. 2, pp. 165–173, 2001 - Prion and prejudice: normal protein and the synapse
Trends in Neurosciences, vol. 24, no. 2, pp. 85–90, 2001 - d-opioid receptors inhibit neurogenic intestinal secretion evoked by mast cell degranulation and type I hypersensitivity
Journal of Neuroimmunology, vol. 112, no. 1-2, pp. 89–96, 2001 - Opioid, cannabinoid and vanilloid receptor localization on porcine cultured myenteric neurons
Neuroscience Letters, vol. 308, no. 3, pp. 153–156, 2001 - BSE did not cause variant CJD: an alternative cause related to post-industrial environmental contamination
Medical Hypotheses, vol. 57, no. 5, pp. 555–560, 2001 - Astrocytes Regulate N-Methyl-D-aspartate Receptor Subunit Composition Increasing Neuronal Sensitivity to Excitotoxicity
Journal of Biological Chemistry, vol. 276, no. 25, pp. 22446–22452, 2001 - Copper and prion diseases
Biochemical Society Transactions, vol. 30, no. 4, p. 742, 2001 - Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations
European Journal of Biochemistry, vol. 268, no. 23, pp. 6155–6164, 2001 - Antioxidant activity related to copper binding of native prion protein
Journal of Neurochemistry, vol. 76, no. 1, pp. 69–76, 2001 - Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein
Journal of Neurochemistry, vol. 76, no. 2, pp. 565–572, 2001 - Inhibition of tumour necrosis factor-alpha (TNFalpha)-induced NF-kappaB p52 converts the metabolic effects of microglial-derived TNFalpha on mouse cerebellar neurones to neurotoxicity
Journal of Neurochemistry, vol. 76, no. 5, pp. 1431–1438, 2001 - Aberrant metal binding by prion protein in human prion disease
Journal of Neurochemistry, vol. 78, no. 6, pp. 1400–1408, 2001 - Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
Journal of Neurochemistry, vol. 79, no. 3, pp. 689–698, 2001 - Observations from the CDC. Community Prevention Study: Contributions to Women's Health and Prevention Research
Journal of Women's Health Gender-Based Medicine, vol. 10, no. 10, pp. 913–920, 2001 - Consequences of manganese replacement of copper for prion protein function and proteinase resistance
The EMBO Journal, vol. 19, no. 6, pp. 1180–1186, 2000 - Perceived Barriers to Exercise and Stage of Exercise Adoption in Older Women of Different Racial/Ethnic Groups
Women and Health, vol. 30, no. 4, pp. 61–76, 2000 - Functional and structural differences between the prion protein from two alleles prnpa and prnpb of mouse
European Journal of Biochemistry, vol. 267, no. 8, pp. 2452–2459, 2000 - Altered toxicity of the prion protein peptide PrP106?126 carrying the Ala117?Val mutation
Biochemical Journal, vol. 346, no. 3, p. 785, 2000 - PrPSc-like prion protein peptide inhibits the function of cellular prion protein
Biochemical Journal, vol. 352, no. 2, p. 511, 2000 - Nature Biotechnology, vol. 18, no. 2, pp. 168–171, 2000
- Orphanin FQ/nociceptin: a novel neuromodulator of gastrointestinal function?
Peptides, vol. 21, no. 7, pp. 999–1005, 2000 - Expression of nociceptin/OFQ receptor and prepro-nociceptin/OFQ in lymphoid tissues
Peptides, vol. 21, no. 12, pp. 1865–1870, 2000 - Promoting physical activity in rural communities Walking trail access, use, and effects
American Journal of Preventive Medicine, vol. 18, no. 3, pp. 235–241, 2000 - Prion Protein Peptides: Optimal Toxicity and Peptide Blockade of Toxicity
Molecular and Cellular Neuroscience, vol. 15, no. 1, pp. 66–78, 2000 - Neuronal Release of Vasoactive Intestinal Peptide Is Important to Astrocytic Protection of Neurons from Glutamate Toxicity
Molecular and Cellular Neuroscience, vol. 15, no. 5, pp. 465–475, 2000 - A Model for the Mechanism of Astrogliosis in Prion Disease
Molecular and Cellular Neuroscience, vol. 16, no. 3, pp. 221–232, 2000 - Copper Has Differential Effect on Prion Protein with Polymorphism of Position 129
Biochemical and Biophysical Research Communications, vol. 269, no. 3, pp. 726–731, 2000 - Prion Disease: A Loss of Antioxidant Function?
Biochemical and Biophysical Research Communications, vol. 275, no. 2, pp. 249–252, 2000 - Copper Refolding of Prion Protein
Biochemical and Biophysical Research Communications, vol. 276, no. 3, pp. 1217–1224, 2000 - Localization of CB 1 -cannabinoid receptor immunoreactivity in the porcine enteric nervous system
Cell and Tissue Research, vol. 302, no. 1, pp. 73–80, 2000 - Community Interventions to Promote Proper Nutrition and Physical Activity among Youth
Preventive Medicine, vol. 31, no. 2, pp. S138–S149, 2000 - Evaluation of substance P as a neurotransmitter in equine jejunum
American Journal of Veterinary Research, vol. 61, no. 10, pp. 1178–1184, 2000 - In vitro evaluation of intraluminal factors that may alter intestinal permeability in ponies with carbohydrate-induced laminitis
American Journal of Veterinary Research, vol. 61, no. 8, pp. 858–861, 2000 - MOVEMENT AND TERRITORIALITY OF WINTERING HERMIT THRUSHES IN SOUTHEASTERN LOUISIANA
The Wilson Bulletin, vol. 112, no. 3, p. 347, 2000 - Catecholaminergic, cholinergic and peptidergic innervation of gut-associated lymphoid tissue in porcine jejunum and ileum
Cell and Tissue Research, vol. 298, no. 2, pp. 275–286, 1999 - Neurons Depend on Astrocytes in a Coculture System for Protection from Glutamate Toxicity
Molecular and Cellular Neuroscience, vol. 13, no. 5, pp. 379–389, 1999 - Selective Oxidation of Methionine Residues in Prion Proteins
Biochemical and Biophysical Research Communications, vol. 259, no. 2, pp. 352–355, 1999 - Prion protein expression aids cellular uptake and veratridine-induced release of copper
Journal of Neuroscience Research, vol. 58, no. 5, pp. 717–725, 1999 - Astrocytic glutamate uptake and prion protein expression
Glia, vol. 25, no. 3, pp. 282–292, 1999 - Physical activity patterns of Chippewa and Menominee Indians The Inter-Tribal Heart Project
American Journal of Preventive Medicine, vol. 17, no. 3, pp. 189–197, 1999 - Cloning, expression and functional role of a nociceptin/orphanin FQ receptor in the porcine gastrointestinal tract
European Journal of Pharmacology, vol. 365, no. 2-3, pp. 281–289, 1999 - Potentiation of anaphylaxis in guinea pig ileal mucosa by a selective d-opioid receptor agonist
European Journal of Pharmacology, vol. 379, no. 1, pp. 81–85, 1999 - Comment on: Neurotoxicity of prion peptide 106–126 not confirmed by Beat Kunz, Erika Sandmeier, Philipp Christen, FEBS Letters 458 (1999) 65–68
FEBS Letters, vol. 460, no. 3, pp. 559–560, 1999 - Journal of Neurocytology, vol. 28, no. 2, pp. 149–159, 1999
- Histochemical Journal, vol. 31, no. 11, pp. 711–716, 1999
- Normal prion protein has an activity like that of superoxide dismutase
Biochemical Journal, vol. 344, no. 1, p. 1, 1999 - Dependence of Neurones on Astrocytes in a Coculture System RendersNeurones Sensitive to Transforming Growth Factor \gb\1-Induced GlutamateToxicity
Journal of Neurochemistry, vol. 72, no. 3, pp. 943–953, 1999 - Prion Protein Peptide Neurotoxicity Can Be Mediated by Astrocytes
Journal of Neurochemistry, vol. 73, no. 3, pp. 1105–1113, 1999 - Journal of Neurocytology, vol. 27, no. 2, pp. 109–118, 1998
- Digestive Diseases and Sciences, vol. 43, no. 7, pp. 1402–1410, 1998
- The porcine mu opioid receptor: molecular cloning and mRNA distribution in lymphoid tissues
Journal of Neuroimmunology, vol. 90, no. 2, pp. 192–198, 1998 - A method for long term culture of murine type 2 astrocytes
Journal of Neuroscience Methods, vol. 79, no. 2, pp. 161–167, 1998 - Cellular effects of a neurotoxic prion protein peptide are related to its ?-sheet content
Neuroscience Research Communications, vol. 23, no. 2, pp. 119–128, 1998 - Prion protein fragment interacts with PrP-deficient cells
Journal of Neuroscience Research, vol. 52, no. 3, pp. 260–267, 1998 - Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide
Journal of Neuroscience Research, vol. 54, no. 3, pp. 331–340, 1998 - Medical Costs and Lost Productivity from Health Conditions at Volatile Organic Compound-Contaminated Superfund Sites,
Environmental Research, vol. 79, no. 1, pp. 9–19, 1998 - A Prion Protein Fragment Primes Type 1 Astrocytes to Proliferation Signals from Microglia
Neurobiology of Disease, vol. 4, no. 6, pp. 410–422, 1998 - Effects of oxidative stress on prion protein expression in PC12 cells
International Journal of Developmental Neuroscience, vol. 15, no. 8, pp. 961–972, 1997 - Nature, vol. 390, no. 6661, pp. 684–687, 0