David R. Brown

David R. Brown was born in Sydney, Australia, but currently works in the Department of Biology and Biochemistry at the University of Bath in England. Professor Brown’s main interest is the basic mechanisms behind neurodegenerative disorders. In particular, he has shown that metals bind to a variety of proteins, including the prion protein. His current work has focussed on metal binding to a-synculein. He serves as an editor for the Journal of Neurochemistry and is currently a Member of the prestigious SEAC committee (Spongiform Encephalopathy Advisory Committee), advising the UK government on issues related to bovine spongiform encephalopathy and Creutzfeldt–Jakob disease.

Biography Updated on 13 August 2007

Articles in Scholarly Journals [Incomplete List]

  1. Anterograde axonal transport of chicken cellular prion protein (PrPc) in vivo requires its N-terminal part
    Journal of Neuroscience Research, vol. 85, no. 12, pp. 2567–2579, 2007
  2. Real-time kinetics of discontinuous and highly conformational metal-ion binding sites of prion protein
    JBIC Journal of Biological Inorganic Chemistry, vol. 12, no. 5, pp. 711–720, 2007
  3. Dual polarisation interferometry analysis of copper binding to the prion protein: Evidence for two folding states
    Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, vol. 1774, no. 7, pp. 920–927, 2007
  4. Prion protein does not redox-silence Cu2+, but is a sacrificial quencher of hydroxyl radicals
    Free Radical Biology and Medicine, vol. 42, no. 1, pp. 79–89, 2007
  5. The healthy brain and our aging population: Translating science to public health practice
    Alzheimer's and Dementia, vol. 3, no. 2, pp. S3–S5, 2007
  6. Regulation of Prion Protein Expression by Noncoding Regions of the Prnp Gene
    Journal of Molecular Biology, vol. 368, no. 4, pp. 915–927, 2007
  7. Autonomic neurotransmitters modulate immunoglobulin A secretion in porcine colonic mucosa
    Journal of Neuroimmunology, vol. 185, no. 1-2, pp. 20–28, 2007
  8. Anatomical evidence for enteric neuroimmune interactions in Peyer’s patches
    Journal of Neuroimmunology, vol. 185, no. 1-2, pp. 64–74, 2007
  9. Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine
    Veterinary Microbiology, vol. 120, no. 3-4, pp. 328–333, 2007
  10. NMR characterization of the pH 4 ß-intermediate of the prion protein: the N-terminal half of the protein remains unstructured and retains a high degree of flexibility
    Biochemical Journal, vol. 401, no. 2, p. 533, 2007
  11. An Assessment of Risk from Particulate Released from Outdoor Wood Boilers
    Human and Ecological Risk Assessment, vol. 13, no. 1, pp. 191–208, 2007
  12. Response to Christopher M. Long and Peter Valberg (2007) "Comments on Brown et al. (2007) An Assessment of Risk from Particulate Released from Outdoor Wood Boilers." Hum. Ecol. Risk Assess. 13(1)
    Human and Ecological Risk Assessment, vol. 13, no. 3, pp. 686–690, 2007
  13. Ancient conserved domain protein-1 binds copper and modifies its retention in cells
    Journal of Neurochemistry, vol. 0, no. 0, pp. 070702072507004–???, 2007
  14. Introduction: Copper and amyloid fibril formation
    FEBS Journal, vol. 274, no. 15, pp. 3755–3755, 2007
  15. Interactions between metals and ?-synuclein???function or artefact?
    FEBS Journal, vol. 274, no. 15, pp. 3766–3774, 2007
  16. Modelling neurodegeneration in prion disease ? applications for drug development
    Expert Opinion on Drug Discovery, vol. 2, no. 6, pp. 777–788, 2007
  17. WHAT IS A WINTER FLOATER? CAUSES, CONSEQUENCES, AND IMPLICATIONS FOR HABITAT SELECTION
    The Condor, vol. 109, no. 3, p. 548, 2007
  18. Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie and bovine spongiform encephalopathy
    Journal of Animal Science, vol. 85, no. 6, pp. 1596–1609, 2007
  19. Genetic Manipulation of Intraspinal Plasticity after Spinal Cord Injury Alters the Severity of Autonomic Dysreflexia
    Journal of Neuroscience, vol. 26, no. 11, pp. 2923–2932, 2006
  20. Mouse galectin-1 inhibits the toxicity of glutamate by modifying NR1 NMDA receptor expression
    European Journal of Neuroscience, vol. 24, no. 11, pp. 3017–3025, 2006
  21. Prion protein reduces both oxidative and non-oxidative copper toxicity
    Journal of Neurochemistry, vol. 98, no. 3, pp. 677–689, 2006
  22. Copper-dependent co-internalization of the prion protein and glypican-1
    Journal of Neurochemistry, vol. 98, no. 5, pp. 1445–1457, 2006
  23. Empirical and theoretical analysis of the extremely low frequency arterial blood pressure power spectrum in unanesthetized rat
    AJP: Heart and Circulatory Physiology, vol. 291, no. 6, pp. H2816–H2824, 2006
  24. Synthesis and Characterization of Luminescent Yttrium Oxide Doped with Tm and Yb
    Journal of the American Ceramic Society, vol. 89, no. 3, pp. 926–931, 2006
  25. Experimental fruit removal does not affect territory structure of wintering Hermit Thrushes
    Journal of Field Ornithology, vol. 77, no. 4, pp. 404–408, 2006
  26. High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation
    FEBS Journal, vol. 273, no. 18, pp. 4250–4263, 2006
  27. Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system
    Molecular and Cellular Neuroscience, vol. 31, no. 1, pp. 97–108, 2006
  28. serovar Choleraesuis infection of the porcine jejunal Peyer's patch rapidly induces IL-1ß and IL-8 expression
    Veterinary Immunology and Immunopathology, vol. 109, no. 1-2, pp. 1–11, 2006
  29. Differential effects of clathrin and actin inhibitors on internalization of Escherichia coli and Salmonella choleraesuis in porcine jejunal Peyer's patches
    Veterinary Microbiology, vol. 113, no. 1-2, pp. 117–122, 2006
  30. Mucosally-directed adrenergic nerves and sympathomimetic drugs enhance non-intimate adherence of Escherichia coli O157:H7 to porcine cecum and colon
    European Journal of Pharmacology, vol. 539, no. 1-2, pp. 116–124, 2006
  31. Hydrogen peroxide cleavage of the prion protein generates a fragment able to initiate polymerisation of full length prion protein
    The International Journal of Biochemistry & Cell Biology, vol. 38, no. 8, pp. 1429–1440, 2006
  32. Food supply controls the body condition of a migrant bird wintering in the tropics
    Oecologia, vol. 149, no. 1, pp. 22–32, 2006
  33. Copper binding is the governing determinant of prion protein turnover
    Molecular and Cellular Neuroscience, vol. 30, no. 2, pp. 186–196, 2005
  34. Mucosal vaccination delays or prevents prion infection via an oral route
    Neuroscience, vol. 133, no. 2, pp. 413–421, 2005
  35. Mediation of neurogenic ion transport by acetylcholine, prostanoids and 5-hydroxytryptamine in porcine ileum
    European Journal of Pharmacology, vol. 519, no. 3, pp. 285–289, 2005
  36. Probing Copper2+ Binding to the Prion Protein Using Diamagnetic Nickel2+ and 1H NMR: The Unstructured N terminus Facilitates the Coordination of Six Copper2+ Ions at Physiological Concentrations
    Journal of Molecular Biology, vol. 346, no. 5, pp. 1393–1407, 2005
  37. High Affinity Binding between Copper and Full-length Prion Protein Identified by Two Different Techniques
    Journal of Biological Chemistry, vol. 280, no. 52, pp. 42750–42758, 2005
  38. Adrenocorticotrophic hormone modulates Escherichia coli O157:H7 adherence to porcine colonic mucosa
    Stress: The International Journal on the Biology of Stress, vol. 8, no. 3, pp. 185–190, 2005
  39. Consequences, Ethical Obligations, IRIS, NAS Reviews and Perchlorate in Drinking Water
    Human and Ecological Risk Assessment, vol. 11, no. 3, pp. 477–482, 2005
  40. Differential acquisition of specific components of a classically conditioned arterial blood pressure response in rat
    AJP: Regulatory, Integrative and Comparative Physiology, vol. 289, no. 3, pp. R784–R788, 2005
  41. An Aggregation-Specific Enzyme-Linked Immunosorbent Assay: Detection of Conformational Differences between Recombinant PrP Protein Dimers and PrPSc Aggregates
    Journal of Virology, vol. 79, no. 19, pp. 12355–12364, 2005
  42. AT1-receptor antagonism reverses the blood pressure elevation associated with diet-induced obesity
    AJP: Regulatory, Integrative and Comparative Physiology, vol. 289, no. 1, pp. R181–R186, 2005
  43. Physical Activity among Adults ???50 yr with and without Disabilities, BRFSS 2001
    Medicine & Science in Sports & Exercise, vol. 37, no. 4, pp. 620–629, 2005
  44. Behavioral Response of Resident Jamaican Birds to Dry Season Food Supplementation1
    Biotropica, vol. 0, no. 0, p. 051128134355004, 2005
  45. Therapeutics and Prion Disease: Can Immunisation or Drugs be Effective?
    Mini Reviews in Medicinal Chemistry, vol. 5, no. 4, pp. 361–366, 2005
  46. The use of peptides that pick up prions: protection or poison?
    Expert Opinion on Therapeutic Patents, vol. 15, no. 9, pp. 1287–1290, 2005
  47. Frugivory by Wintering Hermit Thrush In Louisiana
    Southeastern Naturalist, vol. 4, no. 4, p. 627, 2005
  48. Lessons from the porcine enteric nervous system
    Neurogastroenterology and Motility, vol. 16, no. s1, pp. 50–54, 2004
  49. Associations between Physical Activity Dose and Health-Related Quality of Life
    Medicine & Science in Sports & Exercise, pp. 890–896, 2004
  50. Adrenergic modulation of Escherichia coli O157:H7 adherence to the colonic mucosa
    AJP: Gastrointestinal and Liver Physiology, vol. 287, no. 6, pp. G1238–G1246, 2004
  51. Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension
    AJP: Regulatory, Integrative and Comparative Physiology, vol. 287, no. 4, pp. R943–R949, 2004
  52. Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors
    NeuroReport, vol. 15, no. 3, pp. 483–486, 2004
  53. Journal of Medicinal Chemistry, vol. 47, no. 22, pp. 5515–5534, 2004
  54. Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases
    Dalton Transactions, no. 13, p. 1907, 2004
  55. Role of the prion protein in copper turnover in astrocytes
    Neurobiology of Disease, vol. 15, no. 3, pp. 534–543, 2004
  56. Astrocytic regulation of NMDA receptor subunit composition modulates the toxicity of prion peptide PrP106–126
    Molecular and Cellular Neuroscience, vol. 25, no. 1, pp. 181–191, 2004
  57. Prion protein fate governed by metal binding
    Biochemical and Biophysical Research Communications, vol. 325, no. 3, pp. 1005–1012, 2004
  58. BSE and vCJD cause disturbance to uric acid levels
    Experimental Neurology, vol. 190, no. 1, pp. 233–244, 2004
  59. Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region
    Journal of Inorganic Biochemistry, vol. 98, no. 1, pp. 133–143, 2004
  60. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice
    The Journal of Pathology, vol. 203, no. 1, pp. 603–608, 2004
  61. Physical Activity and Body Mass Index Among US Adolescents: Youth Risk Behavior Survey, 1999
    Archives of Pediatrics and Adolescent Medicine, vol. 157, no. 8, pp. 816–820, 2003
  62. Characterization of specific d-opioid binding sites in the distal small intestine of swine
    European Journal of Pharmacology, vol. 482, no. 1-3, pp. 111–116, 2003
  63. Conformational exposure: a new handle on prions
    The Lancet, vol. 362, no. 9388, pp. 929–930, 2003
  64. Neuromodulation of enteropathogen internalization in Peyer's patches from porcine jejunum
    Journal of Neuroimmunology, vol. 141, no. 1-2, pp. 74–82, 2003
  65. Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106–126
    Neuroscience Letters, vol. 336, no. 3, pp. 159–162, 2003
  66. Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa
    British Journal of Pharmacology, vol. 140, no. 4, Article ID 0705485, 9 pages, 2003
  67. Analysis of doppel protein toxicity
    Molecular and Cellular Neuroscience, vol. 23, no. 1, pp. 144–155, 2003
  68. Biochemistry, vol. 42, no. 25, pp. 7675–7681, 2003
  69. Mapping the functional domain of the prion protein
    European Journal of Biochemistry, vol. 270, no. 16, pp. 3368–3376, 2003
  70. A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation
    European Journal of Neuroscience, vol. 18, no. 3, pp. 571–579, 2003
  71. Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein
    Biochemical Journal, vol. 370, no. 1, p. 81, 2003
  72. Prion protein expression modulates neuronal copper content
    Journal of Neurochemistry, vol. 87, no. 2, pp. 377–385, 2003
  73. Copper Chelation Delays the Onset of Prion Disease
    Journal of Biological Chemistry, vol. 278, no. 47, pp. 46199–46202, 2003
  74. Catecholamines Modulate Escherichia coli O157:H7 Adherence to Murine Cecal Mucosa
    Shock, vol. 20, no. 2, pp. 183–188, 2003
  75. Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126
    NeuroReport, vol. 14, no. 13, pp. 1743–1745, 2003
  76. Kinin-Induced Anion-Dependent Secretion in Porcine Ileum: Characterization and Involvement of Opioid- and Cannabinoid-Sensitive Enteric Neural Circuits
    Journal of Pharmacology and Experimental Therapeutics, vol. 305, no. 2, pp. 733–739, 2003
  77. Characterization of Specific Opioid Binding Sites in Neural Membranes from the Myenteric Plexus of Porcine Small Intestine
    Journal of Pharmacology and Experimental Therapeutics, vol. 308, no. 1, pp. 385–393, 2003
  78. Predominance of delta -Opioid-Binding Sites in the Porcine Enteric Nervous System
    Journal of Pharmacology and Experimental Therapeutics, vol. 300, no. 3, pp. 900–909, 2002
  79. Physical activity, sports participation, and suicidal behavior among college students
    Medicine & Science in Sports & Exercise, vol. 34, no. 7, pp. 1087–1096, 2002
  80. Endocannabinoids as physiological regulators of colonic propulsion in mice
    Gastroenterology, vol. 123, no. 1, pp. 227–234, 2002
  81. Mayhem of the multiple mechanisms: modelling neurodegeneration in prion disease
    Journal of Neurochemistry, vol. 82, no. 2, pp. 209–215, 2002
  82. Biochemistry, vol. 41, no. 22, pp. 6891–6896, 2002
  83. Metal imbalance and compromised antioxidant function are early changes in prion disease
    Biochemical Journal, vol. 362, no. 1, p. 253, 2002
  84. Gastric antisecretory role and immunohistochemical localization of cannabinoid receptors in the rat stomach
    British Journal of Pharmacology, vol. 135, no. 7, Article ID 0704625, 8 pages, 2002
  85. Cannabinoids throw up a conundrum
    British Journal of Pharmacology, vol. 137, no. 5, Article ID 0704913, 2 pages, 2002
  86. Active bicarbonate-dependent secretion evoked by 5-hydroxytryptamine in porcine ileal mucosa is mediated by opioid-sensitive enteric neurons
    European Journal of Pharmacology, vol. 451, no. 2, pp. 185–190, 2002
  87. High Extracellular Potassium Protects against the Toxicity of Cytosine Arabinoside but Is Not Required for the Survival of Cerebellar Granule Cells in Vitro
    Molecular and Cellular Neuroscience, vol. 19, no. 2, pp. 281–291, 2002
  88. Relationship of Satisfaction with Body Size and Trying to Lose Weight in a National Survey of Overweight and Obese Women Aged 40 and Older, United States
    Preventive Medicine, vol. 35, no. 4, pp. 390–396, 2002
  89. Chemical coding of neurons expressing δ- and κ-opioid receptor and type I vanilloid receptor immunoreactivities in the porcine ileum
    Cell and Tissue Research, vol. 307, no. 1, pp. 23–33, 2002
  90. Demographic Effects of Habitat Selection by Hermit Thrushes Wintering in a Pine Plantation Landscape
    The Journal of Wildlife Management, vol. 66, no. 2, p. 407, 2002
  91. Copper-Dependent Functions for the Prion Protein
    Molecular Biotechnology, vol. 22, no. 2, pp. 165–178, 2002
  92. Molecular Advances in Understanding Inherited Prion Diseases
    Molecular Neurobiology, vol. 25, no. 3, pp. 287–302, 2002
  93. Microglia and prion disease
    Microscopy Research and Technique, vol. 54, no. 2, pp. 71–80, 2001
  94. Lack of prion protein expression results in a neuronal phenotype sensitive to stress
    Journal of Neuroscience Research, vol. 67, no. 2, pp. 211–224, 2001
  95. Desiccation Tolerance in Human Cells
    Cryobiology, vol. 42, no. 3, pp. 207–217, 2001
  96. Induction of HO-1 and NOS in Doppel-Expressing Mice Devoid of PrP: Implications for Doppel Function
    Molecular and Cellular Neuroscience, vol. 17, no. 4, pp. 768–775, 2001
  97. Air quality measures and public health policy
    Public Health Reports, vol. 116, no. 1, pp. 61–63, 2001
  98. Opioid receptors on bone marrow neutrophils modulate chemotaxis and CD11b/CD18 expression
    European Journal of Pharmacology, vol. 414, no. 2-3, pp. 289–294, 2001
  99. Copper and prion disease
    Brain Research Bulletin, vol. 55, no. 2, pp. 165–173, 2001
  100. Prion and prejudice: normal protein and the synapse
    Trends in Neurosciences, vol. 24, no. 2, pp. 85–90, 2001
  101. d-opioid receptors inhibit neurogenic intestinal secretion evoked by mast cell degranulation and type I hypersensitivity
    Journal of Neuroimmunology, vol. 112, no. 1-2, pp. 89–96, 2001
  102. Opioid, cannabinoid and vanilloid receptor localization on porcine cultured myenteric neurons
    Neuroscience Letters, vol. 308, no. 3, pp. 153–156, 2001
  103. BSE did not cause variant CJD: an alternative cause related to post-industrial environmental contamination
    Medical Hypotheses, vol. 57, no. 5, pp. 555–560, 2001
  104. Astrocytes Regulate N-Methyl-D-aspartate Receptor Subunit Composition Increasing Neuronal Sensitivity to Excitotoxicity
    Journal of Biological Chemistry, vol. 276, no. 25, pp. 22446–22452, 2001
  105. Copper and prion diseases
    Biochemical Society Transactions, vol. 30, no. 4, p. 742, 2001
  106. Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations
    European Journal of Biochemistry, vol. 268, no. 23, pp. 6155–6164, 2001
  107. Antioxidant activity related to copper binding of native prion protein
    Journal of Neurochemistry, vol. 76, no. 1, pp. 69–76, 2001
  108. Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein
    Journal of Neurochemistry, vol. 76, no. 2, pp. 565–572, 2001
  109. Inhibition of tumour necrosis factor-alpha (TNFalpha)-induced NF-kappaB p52 converts the metabolic effects of microglial-derived TNFalpha on mouse cerebellar neurones to neurotoxicity
    Journal of Neurochemistry, vol. 76, no. 5, pp. 1431–1438, 2001
  110. Aberrant metal binding by prion protein in human prion disease
    Journal of Neurochemistry, vol. 78, no. 6, pp. 1400–1408, 2001
  111. Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
    Journal of Neurochemistry, vol. 79, no. 3, pp. 689–698, 2001
  112. Observations from the CDC. Community Prevention Study: Contributions to Women's Health and Prevention Research
    Journal of Women's Health Gender-Based Medicine, vol. 10, no. 10, pp. 913–920, 2001
  113. Consequences of manganese replacement of copper for prion protein function and proteinase resistance
    The EMBO Journal, vol. 19, no. 6, pp. 1180–1186, 2000
  114. Perceived Barriers to Exercise and Stage of Exercise Adoption in Older Women of Different Racial/Ethnic Groups
    Women and Health, vol. 30, no. 4, pp. 61–76, 2000
  115. Functional and structural differences between the prion protein from two alleles prnpa and prnpb of mouse
    European Journal of Biochemistry, vol. 267, no. 8, pp. 2452–2459, 2000
  116. Altered toxicity of the prion protein peptide PrP106?126 carrying the Ala117?Val mutation
    Biochemical Journal, vol. 346, no. 3, p. 785, 2000
  117. PrPSc-like prion protein peptide inhibits the function of cellular prion protein
    Biochemical Journal, vol. 352, no. 2, p. 511, 2000
  118. Nature Biotechnology, vol. 18, no. 2, pp. 168–171, 2000
  119. Orphanin FQ/nociceptin: a novel neuromodulator of gastrointestinal function?
    Peptides, vol. 21, no. 7, pp. 999–1005, 2000
  120. Expression of nociceptin/OFQ receptor and prepro-nociceptin/OFQ in lymphoid tissues
    Peptides, vol. 21, no. 12, pp. 1865–1870, 2000
  121. Promoting physical activity in rural communities Walking trail access, use, and effects
    American Journal of Preventive Medicine, vol. 18, no. 3, pp. 235–241, 2000
  122. Prion Protein Peptides: Optimal Toxicity and Peptide Blockade of Toxicity
    Molecular and Cellular Neuroscience, vol. 15, no. 1, pp. 66–78, 2000
  123. Neuronal Release of Vasoactive Intestinal Peptide Is Important to Astrocytic Protection of Neurons from Glutamate Toxicity
    Molecular and Cellular Neuroscience, vol. 15, no. 5, pp. 465–475, 2000
  124. A Model for the Mechanism of Astrogliosis in Prion Disease
    Molecular and Cellular Neuroscience, vol. 16, no. 3, pp. 221–232, 2000
  125. Copper Has Differential Effect on Prion Protein with Polymorphism of Position 129
    Biochemical and Biophysical Research Communications, vol. 269, no. 3, pp. 726–731, 2000
  126. Prion Disease: A Loss of Antioxidant Function?
    Biochemical and Biophysical Research Communications, vol. 275, no. 2, pp. 249–252, 2000
  127. Copper Refolding of Prion Protein
    Biochemical and Biophysical Research Communications, vol. 276, no. 3, pp. 1217–1224, 2000
  128. Localization of CB 1 -cannabinoid receptor immunoreactivity in the porcine enteric nervous system
    Cell and Tissue Research, vol. 302, no. 1, pp. 73–80, 2000
  129. Community Interventions to Promote Proper Nutrition and Physical Activity among Youth
    Preventive Medicine, vol. 31, no. 2, pp. S138–S149, 2000
  130. Evaluation of substance P as a neurotransmitter in equine jejunum
    American Journal of Veterinary Research, vol. 61, no. 10, pp. 1178–1184, 2000
  131. In vitro evaluation of intraluminal factors that may alter intestinal permeability in ponies with carbohydrate-induced laminitis
    American Journal of Veterinary Research, vol. 61, no. 8, pp. 858–861, 2000
  132. MOVEMENT AND TERRITORIALITY OF WINTERING HERMIT THRUSHES IN SOUTHEASTERN LOUISIANA
    The Wilson Bulletin, vol. 112, no. 3, p. 347, 2000
  133. Catecholaminergic, cholinergic and peptidergic innervation of gut-associated lymphoid tissue in porcine jejunum and ileum
    Cell and Tissue Research, vol. 298, no. 2, pp. 275–286, 1999
  134. Neurons Depend on Astrocytes in a Coculture System for Protection from Glutamate Toxicity
    Molecular and Cellular Neuroscience, vol. 13, no. 5, pp. 379–389, 1999
  135. Selective Oxidation of Methionine Residues in Prion Proteins
    Biochemical and Biophysical Research Communications, vol. 259, no. 2, pp. 352–355, 1999
  136. Prion protein expression aids cellular uptake and veratridine-induced release of copper
    Journal of Neuroscience Research, vol. 58, no. 5, pp. 717–725, 1999
  137. Astrocytic glutamate uptake and prion protein expression
    Glia, vol. 25, no. 3, pp. 282–292, 1999
  138. Physical activity patterns of Chippewa and Menominee Indians The Inter-Tribal Heart Project
    American Journal of Preventive Medicine, vol. 17, no. 3, pp. 189–197, 1999
  139. Cloning, expression and functional role of a nociceptin/orphanin FQ receptor in the porcine gastrointestinal tract
    European Journal of Pharmacology, vol. 365, no. 2-3, pp. 281–289, 1999
  140. Potentiation of anaphylaxis in guinea pig ileal mucosa by a selective d-opioid receptor agonist
    European Journal of Pharmacology, vol. 379, no. 1, pp. 81–85, 1999
  141. Comment on: Neurotoxicity of prion peptide 106–126 not confirmed by Beat Kunz, Erika Sandmeier, Philipp Christen, FEBS Letters 458 (1999) 65–68
    FEBS Letters, vol. 460, no. 3, pp. 559–560, 1999
  142. Journal of Neurocytology, vol. 28, no. 2, pp. 149–159, 1999
  143. Histochemical Journal, vol. 31, no. 11, pp. 711–716, 1999
  144. Normal prion protein has an activity like that of superoxide dismutase
    Biochemical Journal, vol. 344, no. 1, p. 1, 1999
  145. Dependence of Neurones on Astrocytes in a Coculture System RendersNeurones Sensitive to Transforming Growth Factor \gb\1-Induced GlutamateToxicity
    Journal of Neurochemistry, vol. 72, no. 3, pp. 943–953, 1999
  146. Prion Protein Peptide Neurotoxicity Can Be Mediated by Astrocytes
    Journal of Neurochemistry, vol. 73, no. 3, pp. 1105–1113, 1999
  147. Journal of Neurocytology, vol. 27, no. 2, pp. 109–118, 1998
  148. Digestive Diseases and Sciences, vol. 43, no. 7, pp. 1402–1410, 1998
  149. The porcine mu opioid receptor: molecular cloning and mRNA distribution in lymphoid tissues
    Journal of Neuroimmunology, vol. 90, no. 2, pp. 192–198, 1998
  150. A method for long term culture of murine type 2 astrocytes
    Journal of Neuroscience Methods, vol. 79, no. 2, pp. 161–167, 1998
  151. Cellular effects of a neurotoxic prion protein peptide are related to its ?-sheet content
    Neuroscience Research Communications, vol. 23, no. 2, pp. 119–128, 1998
  152. Prion protein fragment interacts with PrP-deficient cells
    Journal of Neuroscience Research, vol. 52, no. 3, pp. 260–267, 1998
  153. Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide
    Journal of Neuroscience Research, vol. 54, no. 3, pp. 331–340, 1998
  154. Medical Costs and Lost Productivity from Health Conditions at Volatile Organic Compound-Contaminated Superfund Sites,
    Environmental Research, vol. 79, no. 1, pp. 9–19, 1998
  155. A Prion Protein Fragment Primes Type 1 Astrocytes to Proliferation Signals from Microglia
    Neurobiology of Disease, vol. 4, no. 6, pp. 410–422, 1998
  156. Effects of oxidative stress on prion protein expression in PC12 cells
    International Journal of Developmental Neuroscience, vol. 15, no. 8, pp. 961–972, 1997
  157. Nature, vol. 390, no. 6661, pp. 684–687, 0