Madia Trujillo studied medicine at the Universidad de la República, Uruguay, from 1985 to 1995. Before becoming a Medical Doctor, she had started working in the field of reactive oxygen and nitrogen species formation, reactions, and detoxification, in a novel research group directed by Dr. Rafael Radi at the Facultad de Medicine, Universidad de la República, where she started working as a Teacher Assistant. She made her M.S. degree studies on S-nitrosothiol biochemistry and then her Ph.D. degree studies on the mechanisms of reaction of thiol-containing molecules with peroxynitrite, under the supervision of Dr. Rafael Radi. Nowadays, she is an Associate Professor of biochemistry and forms part of the Center for Free Radical and Biomedical Research at the same university. During the last years, Dr. Trujillo and collaborators have been interested in the kinetics and mechanisms of reaction of thiol-containing peroxidases with their peroxide and reducing substrates. In particular, she is mostly interested in peroxidases from infective and pathogenic microorganisms such as Mycobacterium tuberculosis. Her work has contributed to characterize different enzymatic antioxidant systems that could allow the microorganisms to survey under the conditions of oxidative stress associated with macrophage infection.
Biography Updated on 17 October 2011