After originally studying biochemistry at the University of Bristol, Ian Salt obtained his Ph.D. degree in the Department of Biochemistry at the University of Dundee. Whilst at Dundee his studies focused on the intracellular signaling mechanisms that regulate metabolism, in particular the role of the AMP-activated protein kinase (AMPK). Subsequently, AMPK has become the focus of considerable interest as a therapeutic target for the treatment of type 2 diabetes as it has been demonstrated to mimic several actions of insulin, including glucose transport into muscle and downregulation of gluconeogenic genes in liver. After moving to the University of Glasgow, Ian was awarded a British Heart Foundation Intermediate Fellowship, followed by a Diabetes UK R.D. Lawrence Fellowship to study the effects of insulin on endothelial function. Ian is currently a Senior Lecturer in the Institute of Cardiovascular and Medical Sciences at the University of Glasgow. His current research interests are focused on characterizing the molecular mechanisms that underlie the association of obesity, insulin resistance, and cardiovascular disease.
Biography Updated on 23 March 2011