Marco Folini was born in Sondrio, Italy, in 1968. He graduated in biological sciences at the University of Milan in 1994 and received his postgraduate degree in biotechnological applications from the same University in 2003. In 1996, he won the R. Gamba Award from the University of Milan and in 2002 the Young Investigator Award from the Fondazione IRCCS Istituto Nazionale dei Tumori. Since 1997, he has been working at the Department of Experimental Oncology and Molecular Medicine at Fondazione IRCCS Istituto Nazionale dei Tumori. His main research interests are focused on the development of strategies for the inhibition of cancer cell survival factors (i.e., telomerase and survivin) and on the investigation of possible mechanisms of their regulation in human tumour experimental models and clinical specimens. He acquired a good expertise in the design and in vitro synthesis of hammerhead ribozymes directed against telomerase and survivin and of third-generation antisense oligomers and small interfering RNAs as well as in the development of strategies for their intracellular delivery. On this topic he is Coinventor of the patent “Cationic lipids for the transfection of nucleic acid” (Publication no. WO/2006/087752). Recently, his research interests have been extended to the understanding of the role of microRNAs in the pathogenesis of cancer, with the main aim to identify and validate new therapeutic targets. He has been involved as Principal Investigator or coworker in several national and international projects (e.g., AIRC, Fondazione Monzino, Fondazione Cariplo, FIRB-IDEA, 7th EU framework Program). He is the author of about 40 publications in international journals.
Biography Updated on 16 December 2010