Anna Wald
University of Washington, USA
Anna Wald is a Professor in the Departments of Medicine and Epidemiology, and Laboratory Medicine at the University of Washington, Seattle, Wash, USA. She holds an M.D. degree from Mount Sinai School of Medicine and an M.P.H. degree from the University of Washington. She completed training in internal medicine at Boston City Hospital and in infectious diseases at University of Washington. She is the Director of the University of Washington Virology Research Clinic, a clinic dedicated to the study of epidemiology, natural history, and therapeutics for HSV infections. Her research has focused on genital herpes infections, including infections in pregnant women. She has been an Investigator in many clinical trials for novel antiviral agents and prophylactic and therapeutic vaccines for HSV infection. She has had a long-standing interest in HIV-HSV-2 coinfections, both from the view of the clinical management of HIV-HSV-2-coinfected patients and from the public health view of the amplification of HIV epidemic through HSV-2 infections.
Biography Updated on 18 August 2008
Personal Home Page
http://depts.washington.edu/daid/faculty/wald.htm
Articles in Scholarly Journals [Incomplete List]
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American Journal of Obstetrics and Gynecology, vol. 196, no. 1, pp. e13–e14, 2007 - Effect of maternal herpes simplex virus (HSV) serostatus and HSV type on risk of neonatal herpes
Acta Obstetricia et Gynecologica Scandinavica, vol. 86, no. 5, pp. 523–529, 2007 - Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation
Journal of Experimental Medicine, vol. 204, no. 3, pp. 595–603, 2007 - Topical Resiquimod 0.01% Gel Decreases Herpes Simplex Virus Type 2 Genital Shedding: A Randomized, Controlled Trial
The Journal of Infectious Diseases, vol. 195, no. 9, pp. 1324–1331, 2007 - Use of Long-Term Suppressive Acyclovir after Hematopoietic Stem-Cell Transplantation: Impact on Herpes Simplex Virus (HSV) Disease and Drug-Resistant HSV Disease
The Journal of Infectious Diseases, vol. 196, no. 2, pp. 266–270, 2007 - Polymorphisms in TLR2 Are Associated with Increased Viral Shedding and Lesional Rate in Patients with Genital Herpes Simplex Virus Type 2 Infection
The Journal of Infectious Diseases, vol. 196, no. 4, pp. 505–509, 2007 - HSV-2 Serologic Testing in an HMO Population: Uptake and Psychosocial Sequelae
Sexually Transmitted Diseases, vol. 34, no. 9, pp. 718–725, 2007 - Incident and prevalent herpes simplex virus type 2 infection increases risk of HIV acquisition among women in Uganda and Zimbabwe
AIDS, vol. 21, no. 12, pp. 1515–1523, 2007 - Optimizing PCR Positivity Criterion for Detection of Herpes Simplex Virus DNA on Skin and Mucosa
Journal of Clinical Microbiology, vol. 45, no. 5, pp. 1618–1620, 2007 - Longitudinal study of herpes simplex virus type 2 infection using viral dynamic modelling
Sexually Transmitted Infections, vol. 83, no. 5, pp. 359–364, 2007 - One-year acyclovir prophylaxis for preventing varicella-zoster virus disease after hematopoietic cell transplantation: no evidence of rebound varicella-zoster virus disease after drug discontinuation
Blood, vol. 110, no. 8, pp. 3071–3077, 2007 - Genital herpes: antiviral therapy for symptom relief and prevention of transmission
Expert Opinion on Pharmacotherapy, vol. 7, no. 6, pp. 665–675, 2006 - HIV serodiscordant sex partners and the prevalence of human herpesvirus 8 infection among HIV negative men who have sex with men: baseline data from the EXPLORE Study
Sexually Transmitted Infections, vol. 82, no. 3, pp. 229–235, 2006 - Genital HSV-1 infections
Sexually Transmitted Infections, vol. 82, no. 3, pp. 189–190, 2006 - Sequence-Based Methods for Identifying Epidemiologically Linked Herpes Simplex Virus Type 2 Strains
Journal of Clinical Microbiology, vol. 44, no. 7, pp. 2541–2546, 2006 - Fulminant, Acyclovir-Resistant, Herpes Simplex Virus Type 2 Hepatitis in an Immunocompetent Woman
Journal of Clinical Microbiology, vol. 44, no. 4, pp. 1584–1586, 2006 - Comparative Efficacy of Famciclovir and Valacyclovir for Suppression of Recurrent Genital Herpes and Viral Shedding
Sexually Transmitted Diseases, vol. 33, no. 9, pp. 529–533, 2006 - High Risk of Human Immunodeficiency Virus in Men Who Have Sex with Men with Herpes Simplex Virus Type 2 in the EXPLORE Study
American Journal of Epidemiology, vol. 164, no. 8, pp. 733–741, 2006 - Repeat-Region Polymorphisms in the Gene for the Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin-Related Molecule: Effects on HIV-1 Susceptibility
The Journal of Infectious Diseases, vol. 193, no. 5, pp. 698–702, 2006 - Knowledge of Partners' Genital Herpes Protects against Herpes Simplex Virus Type 2 Acquisition
The Journal of Infectious Diseases, vol. 194, no. 1, pp. 42–52, 2006 - Management of Herpes Simplex Virus Type 2 Infection in HIV Type 1-Infected Persons
Clinical Infectious Diseases, vol. 43, no. 3, pp. 347–356, 2006 - Oral Herpes Simplex Virus Type 2 Reactivation in HIV-Positive and -Negative Men
The Journal of Infectious Diseases, vol. 194, no. 4, pp. 420–427, 2006 - Frequent and Asymptomatic Oropharyngeal Shedding of Human Herpesvirus 8 among Immunocompetent Men
The Journal of Infectious Diseases, vol. 195, no. 1, pp. 30–36, 2006 - Targeted prenatal herpes simplex virus testing: Can we identify women at risk of transmission to the neonate?
American Journal of Obstetrics and Gynecology, vol. 194, no. 2, pp. 408–414, 2006 - Maternal herpes simplex virus antibody avidity and risk of neonatal herpes
American Journal of Obstetrics and Gynecology, vol. 195, no. 1, pp. 115–120, 2006 - Clinical correlates of index values in the focus HerpeSelect ELISA for antibodies to herpes simplex virus type 2 (HSV-2)
Journal of Clinical Virology, vol. 36, no. 2, pp. 141–145, 2006 - A randomized controlled trial of a replication defective (gH deletion) herpes simplex virus vaccine for the treatment of recurrent genital herpes among immunocompetent subjects
Vaccine, vol. 24, no. 7, pp. 914–920, 2006 - Human Herpesvirus 8 Infection Among Adolescents in the REACH Cohort
Archives of Pediatrics and Adolescent Medicine, vol. 160, no. 9, pp. 937–942, 2006 - Differentiation of herpes simplex virus types 1 and 2 in clinical samples by a real-time taqman PCR assay
Journal of Medical Virology, vol. 76, no. 3, pp. 350–355, 2005 - Risk factors for herpes simplex virus transmission to pregnant women: A couples study
American Journal of Obstetrics and Gynecology, vol. 193, no. 6, pp. 1891–1899, 2005 - A Population-Based Study of Primary Human Herpesvirus 6 Infection
New England Journal of Medicine, vol. 352, no. 8, pp. 768–776, 2005 - Acyclovir Sensitivity of Sequential Herpes Simplex Virus Type 2 Isolates from the Genital Mucosa of Immunocompetent Women
The Journal of Infectious Diseases, vol. 192, no. 6, pp. 1102–1107, 2005 - Herpes Simplex Virus Type 2 (HSV-2) Western Blot Confirmatory Testing Among Men Testing Positive for HSV-2 Using the Focus Enzyme-Linked Immunosorbent Assay in a Sexually Transmitted Disease Clinic
Sexually Transmitted Diseases, vol. 32, no. 12, pp. 771–777, 2005 - The psychosocial impact of serological herpes simplex type 2 testing in an urban HIV clinic
Sexually Transmitted Infections, vol. 81, no. 4, pp. 309–315, 2005 - Valacyclovir reduced genital herpes transmission in couples discordant for herpes simplex virus type 2 infection
Evidence-Based Medicine, vol. 9, no. 5, pp. 146–146, 2004 - Oral shedding of herpes simplex virus type 2
Sexually Transmitted Infections, vol. 80, no. 4, pp. 272–276, 2004 - Type-specific testing for herpes simplex virus
Expert Review of Molecular Diagnostics, vol. 4, no. 4, pp. 443–453, 2004 - Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment
Blood, vol. 103, no. 5, pp. 1632–1634, 2004 - Failure of cidofovir in HIV-associated multicentric Castleman disease
Blood, vol. 103, no. 11, pp. 4368–4369, 2004 - Development and Use of a Type-Specific Antibody Avidity Test Based on Herpes Simplex Virus Type 2 Glycoprotein G
Sexually Transmitted Diseases, vol. 31, no. 8, pp. 508–515, 2004 - HIV Infection and Human Herpesvirus-8 Oral Shedding Among Men Who Have Sex with Men
JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 35, no. 3, pp. 233–238, 2004 - The Effects of Herpes Simplex Virus-2 on HIV-1 Acquisition and Transmission: A Review of Two Overlapping Epidemics
JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 35, no. 5, pp. 435–445, 2004 - Vitamin A Supplementation and Genital Shedding of Herpes Simplex Virus among HIV-1-Infected Women: A Randomized Clinical Trial
The Journal of Infectious Diseases, vol. 189, no. 8, pp. 1466–1471, 2004 - Frequent Reactivation of Herpes Simplex Virus among HIV-1-Infected Patients Treated with Highly Active Antiretroviral Therapy
The Journal of Infectious Diseases, vol. 190, no. 4, pp. 693–696, 2004 - Valacyclovir and Acyclovir for Suppression of Shedding of Herpes Simplex Virus in the Genital Tract
The Journal of Infectious Diseases, vol. 190, no. 8, pp. 1374–1381, 2004 - Targeting Virological Core Groups: A New Paradigm for Controlling Herpes Simplex Virus Type 2 Epidemics
The Journal of Infectious Diseases, vol. 190, no. 9, pp. 1610–1617, 2004 - Expression of Cutaneous Lymphocyte-Associated Antigen and E-selectin Ligand by Circulating Human Memory CD4+ T Lymphocytes Specific for Herpes Simplex Virus Type 2
The Journal of Infectious Diseases, vol. 191, no. 2, pp. 243–254, 2004 - Once-Daily Valacyclovir to Reduce the Risk of Transmission of Genital Herpes
New England Journal of Medicine, vol. 350, no. 1, pp. 11–20, 2004 - Introduction: Is viral shedding a surrogate marker for transmission of genital herpes?
Antiviral Research, vol. 63, pp. S3–S9, 2004 - Lessons from HIV and hepatitis viruses
Antiviral Research, vol. 63, pp. S11–S18, 2004 - HSV shedding
Antiviral Research, vol. 63, pp. S19–S26, 2004 - HSV-2 transmission
Antiviral Research, vol. 63, pp. S27–S35, 2004 - Invasive aspergillosis before allogeneic hematopoietic stem cell transplantation: 10-year experience at a single transplant center
Biology of Blood and Marrow Transplantation, vol. 10, no. 7, pp. 494–503, 2004 - Cesarean Delivery and Risk of Herpes Simplex Virus Infection
JAMA: The Journal of the American Medical Association, vol. 289, no. 17, pp. 2208–2208, 2003 - Effect of Serologic Status and Cesarean Delivery on Transmission Rates of Herpes Simplex Virus From Mother to Infant
JAMA: The Journal of the American Medical Association, vol. 289, no. 2, pp. 203–209, 2003 - Immunodominance among herpes simplex virus-specific CD8 T cells expressing a tissue-specific homing receptor
Proceedings of the National Academy of Sciences, vol. 100, no. 22, pp. 12899–12904, 2003 - Transferred Herpes Simplex Virus Immunity after Stem-Cell Transplantation: Clinical Implications
The Journal of Infectious Diseases, vol. 187, no. 5, pp. 801–808, 2003 - How Does Herpes Simplex Virus Type 2 Influence Human Immunodeficiency Virus Infection and Pathogenesis?
The Journal of Infectious Diseases, vol. 187, no. 10, pp. 1509–1512, 2003 - Disseminated Sporotrichosis Associated with Treatment with Immunosuppressants and Tumor Necrosis Factor- Antagonists
Clinical Infectious Diseases, vol. 37, no. 6, pp. 838–840, 2003 - Valacyclovir for the Suppression of Recurrent Genital Herpes in Human Immunodeficiency Virus-Infected Subjects
The Journal of Infectious Diseases, vol. 188, no. 7, pp. 1009–1016, 2003 - Polymerase Chain Reaction for Detection of Herpes Simplex Virus (HSV) DNA on Mucosal Surfaces: Comparison with HSV Isolation in Cell Culture
The Journal of Infectious Diseases, vol. 188, no. 9, pp. 1345–1351, 2003 - Correlates of Human Herpesvirus-8 Seropositivity Among U.S. Military Members Recently Infected With Human Immunodeficiency Virus
Sexually Transmitted Diseases, vol. 30, no. 9, pp. 713–718, 2003 - Prevalence and Risk Factors for Infection With Herpes Simplex Virus Type-1 and -2 Among Lesbians
Sexually Transmitted Diseases, vol. 30, no. 12, pp. 890–895, 2003 - Natural History of Genital Herpes Simplex Virus Type 1 Infection
Sexually Transmitted Diseases, vol. 30, no. 2, pp. 174–177, 2003 - Time Course of Seroconversion by HerpeSelect ELISA After Acquisition of Genital Herpes Simplex Virus Type 1 (HSV-1) or HSV-2
Sexually Transmitted Diseases, vol. 30, no. 4, pp. 310–314, 2003 - Psychosocial impact of serological diagnosis of herpes simplex virus type 2: a qualitative assessment
Sexually Transmitted Infections, vol. 79, no. 4, pp. 280–285, 2003 - Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus
Journal of Clinical Investigation, vol. 110, no. 4, pp. 537–548, 2002 - Assessment of a Combined Testing Strategy for Detection of Antibodies to Human Herpesvirus 8 (HHV-8) in Persons with Kaposi's Sarcoma, Persons with Asymptomatic HHV-8 Infection, and Persons at Low Risk for HHV-8 Infection
Journal of Clinical Microbiology, vol. 40, no. 10, pp. 3822–3825, 2002 - Quantitative Stability of DNA after Extended Storage of Clinical Specimens as Determined by Real-Time PCR
Journal of Clinical Microbiology, vol. 40, no. 7, pp. 2609–2611, 2002 - Risk of Human Immunodeficiency Virus Infection in Herpes Simplex Virus Type 2–Seropositive Persons: A Meta-analysis
The Journal of Infectious Diseases, vol. 185, no. 1, pp. 45–52, 2002 - Epidemiology and Outcome of Mould Infections in Hematopoietic Stem Cell Transplant Recipients
Clinical Infectious Diseases, vol. 34, no. 7, pp. 909–917, 2002 - Two-Day Regimen of Acyclovir for Treatment of Recurrent Genital Herpes Simplex Virus Type 2 Infection
Clinical Infectious Diseases, vol. 34, no. 7, pp. 944–948, 2002 - Correlates of Prevalent and Incident Kaposi’s Sarcoma–Associated Herpesvirus Infection in Men Who Have Sex with Men
The Journal of Infectious Diseases, vol. 185, no. 7, pp. 990–993, 2002 - Serological Testing for Herpes Simplex Virus (HSV)–1 and HSV-2 Infection
Clinical Infectious Diseases, vol. 35, no. S2, pp. S173–S182, 2002 - Genital Shedding of Herpes Simplex Virus among Men
The Journal of Infectious Diseases, vol. 186, no. S1, pp. S34–S39, 2002 - HHV-8 infection: a model for reactivation and transmission
Reviews in Medical Virology, vol. 12, no. 1, pp. 47–63, 2002 - Effect of Condoms on Reducing the Transmission of Herpes Simplex Virus Type 2 From Men to Women
JAMA: The Journal of the American Medical Association, vol. 285, no. 24, pp. 3100–3106, 2001 - Effect of Condoms on Reducing Genital Herpes Transmission
JAMA: The Journal of the American Medical Association, vol. 286, no. 17, pp. 2095–2096, 2001 - Genital HSV-2 in asymptomatic subjects
Biomedecine & Pharmacotherapy, vol. 55, no. 1, p. 71, 2001 - Mucosal Shedding of Human Herpesvirus 8
New England Journal of Medicine, vol. 344, no. 9, pp. 690–692, 2001 - Corynebacterium jeikeium bacteremia in bone marrow transplant patients with Hickman catheters
Bone Marrow Transplantation, vol. 27, no. 4, pp. 445–449, 2001 - Demographic rather than behavioral risk factors predict herpes simplex virus type 2 infection in sexually active adolescents
The Pediatric Infectious Disease Journal, vol. 20, no. 4, pp. 422–426, 2001 - Premarket Evaluation of the POCkit HSV-2 Type-Specific Serologic Test in Culture-Documented Cases of Genital Herpes Simplex Virus Type 2
Sexually Transmitted Diseases, vol. 27, no. 5, pp. 266–269, 2000 - Herpes simplex virus: the importance of asymptomatic shedding
Journal of Antimicrobial Chemotherapy, vol. 45, no. 90004, pp. 1–8, 2000 - Reactivation of Genital Herpes Simplex Virus Type 2 Infection in Asymptomatic Seropositive Persons
New England Journal of Medicine, vol. 342, no. 12, pp. 844–850, 2000 - Mucosal Shedding of Human Herpesvirus 8 in Men
New England Journal of Medicine, vol. 343, no. 19, pp. 1369–1377, 2000 - Herpes Simplex Virus Type 1 as a Cause of Genital Herpes: Impact on Surveillance and Prevention
The Journal of Infectious Diseases, vol. 181, no. 4, pp. 1454–1457, 2000 - Herpes Simplex Virus Type 2 Shedding in Human Immunodeficiency Virus–Negative Men Who Have Sex with Men: Frequency, Patterns, and Risk Factors
Clinical Infectious Diseases, vol. 30, no. 2, pp. 261–267, 2000 - Association of Major Histocompatibility Complex Determinants with the Development of Symptomatic and Asymptomatic Genital Herpes Simplex Virus Type 2 Infections
The Journal of Infectious Diseases, vol. 179, no. 5, pp. 1077–1085, 1999 - Antiviral Therapies for Long-term Suppression of Genital Herpes
JAMA: The Journal of the American Medical Association, vol. 281, no. 13, pp. 1169–1170, 1999 - Detection of Herpes Simplex Virus DNA in Semen of Men With Genital HSV-2 Infection
Sexually Transmitted Diseases, vol. 26, no. 1, pp. 1–3, 1999 - An Interactive, Computer-Based Program to Educate Patients About Genital Herpes
Sexually Transmitted Diseases, vol. 26, no. 6, pp. 364–368, 1999 - HERPES SIMPLEX VIRUS–2 INFECTIONAn Emerging Disease?
Infectious Disease Clinics of North America, vol. 12, no. 1, pp. 47–61, 1998 - Virologic Characteristics of Subclinical and Symptomatic Genital Herpes Infections
New England Journal of Medicine, vol. 333, no. 12, pp. 770–775, 1995