Gerald Schlaf studied biology at the University of Goettingen (1985-1992). He completed his final project and Diploma thesis at the Department of Immunogenetics under Professor Eberhard Guenther (May 1990-March 1992). He finished his dissertation (May 1992- November 1995) at the clinic and dispensary of neurology at the Neurochemical/Neuroimmunological Laboratory of Professor Michael Mäder again at the University of Goettingen. He has advanced knowledge in protein chemistry/protein purification, development of immunochemical assays (various ELISA designs), and generation of polyclonal/monoclonal antibodies. From December, 1996, to 1997, he was first employed at the HLA-Laboratory of the University Hospital Halle for the establishment of sequence-based typing (HLA high resolution typing) and establishing some novel ELISA-based assays for anti-HLA antibody detection and specification. From January, 1998 to November, 2004, he held a position at the Department of Immunology (Professor Otto Götze) as an Complement Immunologist. He has advanced knowledge in complement immunology especially anaphylatoxin receptors and the complement inhibitory factors H and I. Regulation of complement activation/homeostasis; generation of recombinant proteins (baculoviral etc.). Since December, 2004, he was employed at the HLA-laboratory of the University Hospital Halle as codirector of the lab which is currently organised as an administrative department under the medical headmaster. His special activities include Investigations on the influence of anti-HLA antibodies on organ rejections and development of alternative crossmatch strategies to circumvent the artifact-based false outcomes of the classical CDC-based procedure. His areas of expertise include protein chemistry, immunochemical assays, complement immunology, and diagnostic aspects/strategies for the detection and specification of anti-HLA antibodies.
Biography Updated on 26 April 2011