Maria P. Macedo0000-0002-2549-0275
Maria Paula Macedo graduated in pharmacy from the Faculty of Pharmacy at the University of Lisbon (Lisbon, Portugal) in 1989 and received her Ph.D. degree in 1996 from the Department of Pharmacology and Therapeutics at the University of Manitoba (Winnipeg, MB, Canada). She was appointed as Professor of pharmacology for pharmacy at the Institute of Health Sciences (Portugal). Since 2000 she has served as Professor of physiology at the Faculty of Medical Sciences at the New University of Lisbon (Lisbon, Portugal). Professor Macedo has been working in research areas related to hepatic vasculature and hepatic control of insulin sensitivity. In life sciences she has awarded several grants as a principal investigator including topics such as the study of meal-induced insulin action sensitisation and the dysfunction of this potentiation in prediabetes and in pathologies related to diabetes as well as the clarification of the molecular mechanisms involved; assessment of subclinical impairments of the autonomic nervous system with impact on glucose and lipid metabolisms; modulation of hepatic inflammatory responses that induce whole-body insulin resistance, targeting Kupffer cells, and nitric oxide production; physiological and pathophysiological alterations of insulin clearance; in vitro studies with skeletal muscle looking at glucose uptake under mimicked controlled or unregulated metabolic conditions; application of environmental and genetic pathological animal models; mathematical modeling of insulin secretion, insulin clearance, and overall glucose fluxes; and followup of the first prevalence study of prediabetes and diabetes in Portugal. Macedo was awarded in recognition of science from the Canadian Pharmacological Society, Western Pharmacological Society, Portuguese Diabetes Association, and Portuguese Association for the Protection of Diabetics. She is actively involved in promotion diabetes research in Portugal by heading the Grupo de Investigação Fundamental e Translacional (GIFT) of the Portuguese Diabetes Association.
Biography Updated on 8 January 2013