Research Article
Biomanufacturing versus Superficial Cell Seeding: Simulation of Chondrocyte Proliferation in a Cylindrical Cartilage Scaffold
Table 1
Properties and parameters for cellular, metabolic, cell growth kinetics and scaffold.
| Property | Value | Reference |
| Cell density | 182 kgm−3 | Bush and Hall, 2001 [10] | Glucose effective diffusivity in cell colony () | m2s−1 |
Galban and Locke, 1999 [9] | Glucose effective diffusivity in the nutrient solution () | m2s−1 | Galban and Locke, 1999 [9] | Glucose partition coefficient | 0.1 | Galban and Locke, 1999 [9] | Cellular maximum consumption rate | 0.03 s−1 | Galban and Locke, 1999 [9] | Initial porosity of the scaffold () | 0.92–0.96 | Freed et al., 1994 [7] | Cell seeding efficiency | 0.60 | Freed et al., 1994 [7] | Initial population of seeded cells | cells | Freed et al., 1994 [7] | Initial volumetric fraction of seeded cells | 0.00548 | Freed et al., 1994 [7] | Cell growth rate coefficient | s−1 | Chung et al., 2006 [5] | Cell death rate coefficient | s−1 | Chung et al., 2006 [5] | Contois saturation coefficient | 1.54 | Galban and Locke, 1999 [9] | Random walk coefficient of cells | m2s−1 | Barocas et al., 1995 [11] |
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