Conference Paper
Critical Analysis of Electromagnetic Hyperthermia Randomized Trials: Dubious Effect and Multiple Biases
Table 15
Final record of randomized clinical trials on hyperthermia in oncology.
| Type | Authors | Year | Localization | Sponsor | Conclusion | Resume | Estimation |
| Superficial HT | Kapp et al. [7] | 1990 | Superficial | Independent | No significant effect | Negative | Perez et al. [5] | 1991 | Superficial | Independent | No significant effect | Negative | Emami et al. [8] | 1992 | Superficial | Independent | No significant effect | Negative | Engin et al. [9] | 1993 | Superficial | Independent | No significant effect | Negative | Vernon et al. [10] | 1996 | Superficial | Hyperthermic | Significant Effect | Dubious | Overgaard et al. [11] | 1996 | Melanoma | Hyperthermic | Significant Effect | Clinically insignificant | Jones et al. [12] | 2005 | Superficial | Hyperthermic | Significant Effect | Dubious |
| Deep HT | Emami et al. [20] | 1996 | Deep seated | Independent | No significant effect | Negative | ā | 2000 | Rectum | Hyperthermic | No significant effect | Negative | van der Zee et al. [21] | Bladder | No significant effect | Negative | ā | Cervix | Significant effect | Clinically insignificant | Harima et al. [24] | 2001 | Cervix | Hyperthermic | Significant effect | Dubious | Vasanthan et al. [15] | 2005 | Cervix | Independent | No significant effect | Extremely negative | Mitsumori et al. [22] | 2007 | NSCLC | Independent | No significant effect | Negative | Issels et al. [23] | 2010 | ST sarcomas |
Hyperthermic | Significant effect | Dubious |
| WBH | Bakhshandeh et al. [40] | 2004 | Pleural mesothelioma | Hyperthermic | No significant effect | Extremely negative |
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