Conference Paper

The History of Hyperthermia Rise and Decline

Table 1

Some results of in vivo experiments on hyperthermia cancer treatment.

YearAnimalTumorCriterionMethod of heating6 hr3 hr1.5 hr1 hr

Prime and Rohdenburg [34] 1921MiceCrocker sarcomaInability of graftingWater bath in vitro42°C 44°C
Westermark [35]1927RatsFlexner sarcoma
Jensen sarcoma
Complete regressionDiathermia in vivo44°C45°C
Johnson [69] 1940 Rats Jensen sarcomaInability of graftingWater bath in vitro43.5°C 45°C
Complete regressionDiathermia in vivo43.5°C45°C (50%)