Immunogenicity and Protective Efficacy of a Polyvalent DNA Vaccine against Human Orthopoxvirus Infections Based on Smallpox Virus Genes
Figure 2
The survival rates of BALB/c mice after triple intraperitoneal (i/p), intramuscular (i/m), intracutaneous (i/c), or subcutaneous (s/c) immunization with (a) pcDNA-F8L or (b) pBKRSV-F8L and intraperitoneal challenge with ectromelia virus strain K1 at a dose of 10 LD50. 10-11 mice in each group were challenged 3 weeks after the last immunization.
