Variant of X-Linked Chronic Granulomatous Disease Revealed by a Severe Burkholderia cepacia Invasive Infection in an Infant
Figure 2
Expression of gp91phox in a patient with the H338R CYBB mutation. Immunostaining of cytochrome b558 in EBV-B cells from a healthy control (C+), an X-linked CGD patient (C−), and the patient (P). Cell surface staining with mAb7D5 (an antibody specific for the extracellular epitope of gp91phox; solid lines); an isotype IgG1 (dotted lines) followed by staining with an Alexa Fluor 488 goat anti-mouse Ig secondary antibody. The results shown are representative of two independent experiments.
