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| Zone | Description | Management |
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| Zone I—midline retroperitoneum | Extends from the aortic hiatus to the sacral promontory and is divided into supramesocolic and inframesocolic zones | All injuries require surgical exploration |
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| Zone II—lateral retroperitoneum | Extends on either side from the renal hila to the pericolic gutters Avoid exploration in blunt trauma | Explore all penetrating trauma |
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| Zone III—pelvic retroperitoneum | Sacral promontory and encompasses the pelvis Explore all penetrating trauma | Explore for expanding hematoma in penetrating trauma |
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