Case Reports in Pathology
Volume 2012 (2012), Article ID 831403, 4 pages
Papillary Renal Carcinoma Arising in an Ectopic Native Kidney and Status after Renal Transplant: A Report of a Unique Case and Review of the Literature
1Department of Pathology and Immunology, Washington University in St. Louis, 660 South Euclid Avenue, P.O. Box 8118, St. Louis, MO 63110, USA
2Department of Pathology, University of California San Diego, San Diego, CA 92103-8720, USA
Received 17 November 2012; Accepted 5 December 2012
Academic Editors: T. Hasebe, O. Hes, M. M. Picken, and N. Seki
Copyright © 2012 Xiangdong Xu and Noel Weidner. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Renal ectopia is an uncommon developmental defect of upper urinary tract. Except for hydronephrosis and urinary calculus formation, it is believed that ectopic kidneys are not more susceptible to diseases compared to the normally positioned kidneys. Primary renal carcinoma in ectopic kidneys is rarely observed. Our literature review identified eight cases in nontransplanted patients; seven were clear-cell carcinoma and one was papillary renal carcinoma. On the other hand, native kidneys of renal transplant patients are fifteen times more likely to develop renal carcinoma than those of nontransplanted patients. Renal malignancy has never been reported in native ectopic kidneys of transplant recipients. We report the first case of a papillary renal carcinoma in a native ectopic kidney of a 30 year-old female, six-year status after renal transplantation.