Research Article

MicroPET/CT Imaging of [18F]-FEPPA in the Nonhuman Primate: A Potential Biomarker of Pathogenic Processes Associated with Anesthetic-Induced Neurotoxicity

Figure 3

A set of representative microPET images (coronal plane) of a control (a) and a treated monkey brain (b) on PND 6. Graph (c) shows the dynamic uptake of [18F]-FEPPA expressed as SUV versus time for each ROI (left temporal lobe) from control and anesthetic-treated monkeys on PND 6 or 7 (n = 4/group). SUV = standard uptake value = average concentration of radioactivity in the ROI (MBq/mL) × body weight in grams/injected dose (MBq). Data are shown as the means ± SEM *P < 0.05.
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(a)
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(b)
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(c)