MicroPET/CT Imaging of [18F]-FEPPA in the Nonhuman Primate: A Potential Biomarker of Pathogenic Processes Associated with Anesthetic-Induced Neurotoxicity
Table 1
Physiological parameters# for baby monkeys in control and treated groups.
Control ()
70% N2O + 1% isoflurane ()
Respiratory rate (breaths per min)
74.1 ± 18.7
66.5 ± 20.3
Expired CO2 (mm Hg)
14.4 ± 3.3
14.5 ± 2.4
Heart Rate (beats per min)
194.4 ± 69.2
163.5 ± 30.2*
O2 saturation (%)
95.2 ± 2.7
97.5 ± 2.4**
Body temperature (°F)
99.2 ± 2.1
92.5 ± 1.9**
Systolic blood pressure (mmHg)
97.2 ± 21
105.5 ± 30.2
Diastolic blood pressure (mmHg)
78.6 ± 18.7
82.7 ± 26.1
Glucose (mg/dL)
54.5 ± 13.2
62.4 ± 16.6
Venous pH
7.28 ± 0.07
7.24 ± 0.08
Hematocrit (%)
45.6 ± 6.4
42.4 ± 11.8
#The values are presented as means ± standard deviations across all time points. * and ** denote statistically significant differences between control and exposed groups with P < 0.05 or P < 0.01, respectively.
