Volume 2012 (2012), Article ID 972085, 3 pages
Effect of Anderson Localization on Auger Destruction of DNA
1Biological Department, Webster University, 470 East Lockwood, Webster Groves, MO 63119, USA
2Theoretical Department, Institute of Polymer Chemistry and Physics, Kadiri 7B, 100128 Tashkent, Uzbekistan
Received 5 November 2012; Accepted 21 November 2012
Academic Editors: K. Nishizawa and M. P. Ponomarenko
Copyright © 2012 N. N. Turaeva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The effect of Anderson localization in DNA on the Auger destruction by the Coulombic explosion at ionized radiation has been theoretically discussed in the present work. The theory of Auger destruction of DNA has been modified taking into account the localized and delocalized electron states in DNA owing to the correlated disorder in a sequence of nucleotides. According to the modified theoretical model of Auger destruction, the dominant ratio of delocalized states to localized states in exon compared to intron results in stronger radiation resistance of exons to ionized irradiation causing the Auger-cascade process than the radiation resistance of introns.