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ISRN Cardiology
Volume 2012 (2012), Article ID 982417, 15 pages
doi:10.5402/2012/982417
Review Article

Primary Prevention of Heart Failure

Javed Butler

Emory University, Atlanta, GA 30322, USA

Received 25 June 2012; Accepted 25 July 2012

Academic Editors: C. Hassager and G. Moe

Copyright © 2012 Javed Butler. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Lloyd-Jones, R. Adams, M. Carnethon et al., “Heart disease and stroke statistics—2009 update: a report from the American heart association statistics committee and stroke statistics subcommittee,” Circulation, vol. 119, no. 3, pp. e21–e181, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. T. E. Owan and M. M. Redfield, “Epidemiology of diastolic heart failure,” Progress in Cardiovascular Diseases, vol. 47, no. 5, pp. 320–332, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. R. S. Vasan, E. J. Benjamin, and D. Levy, “Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective,” Journal of the American College of Cardiology, vol. 26, no. 7, pp. 1565–1574, 1995. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Kalogeropoulos, V. Georgiopoulou, S. B. Kritchevsky et al., “Epidemiology of incident heart failure in a contemporary elderly cohort the health, aging, and body composition study,” Archives of Internal Medicine, vol. 169, no. 7, pp. 708–715, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Butler, “Risk factors for heart failure,” in Congestive Heart Failure, J. D. Hosenpud and B. H. Greenberg, Eds., p. 263, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 3rd edition, 2007.
  6. J. He, L. G. Ogden, L. A. Bazzano, S. Vupputuri, C. Loria, and P. K. Whelton, “Risk factors for congestive heart failure in US men and women: NHANES I epidemiologic follow-up study,” Archives of Internal Medicine, vol. 161, no. 7, pp. 996–1002, 2001. View at Scopus
  7. G. C. Fonarow, “The acute decompensated heart failure national registry (ADHERE): opportunities to improve care of patients hospitalized with acute decompensated heart failure,” Reviews in Cardiovascular Medicine, vol. 4, supplement 7, pp. S21–S30, 2003. View at Scopus
  8. A. W. Haider, M. G. Larson, S. S. Franklin, and D. Levy, “Systolic blood pressure, diastolic blood pressure, and pulse pressure as predictors of risk for congestive heart failure in the Framingham heart study,” Annals of Internal Medicine, vol. 138, no. 1, pp. 10–16, 2003. View at Scopus
  9. S. Kenchaiah, J. C. Evans, D. Levy et al., “Obesity and the risk of heart failure,” The New England Journal of Medicine, vol. 347, no. 5, pp. 305–313, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. L. Djoussé and J. M. Gaziano, “Alcohol consumption and heart failure: a systematic review,” Current Atherosclerosis Reports, vol. 10, no. 2, pp. 117–120, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. J. L. Abramson, S. A. Williams, H. M. Krumholz, and V. Vaccarino, “Moderate alcohol consumption and risk of heart failure among older persons,” The Journal of the American Medical Association, vol. 285, no. 15, pp. 1971–1977, 2001. View at Scopus
  12. L. Djoussé and J. M. Gaziano, “Alcohol consumption and risk of heart failure in the Physicians' health study I,” Circulation, vol. 115, no. 1, pp. 34–39, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Horio, J. Miyazato, K. Kamide, S. Takiuchi, and Y. Kawano, “Influence of low high-density lipoprotein cholesterol on left ventricular hypertrophy and diastolic function in essential hypertension,” American Journal of Hypertension, vol. 16, no. 11 I, pp. 938–944, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. J. Sundström, L. Lind, B. Vessby, B. Andrén, A. Aro, and H. O. Lithell, “Dyslipidemia and an unfavorable fatty acid profile predict left ventricular hypertrophy 20 years later,” Circulation, vol. 103, no. 6, pp. 836–841, 2001. View at Scopus
  15. K. K. L. Ho, J. L. Pinsky, W. B. Kannel, and D. Levy, “The epidemiology of heart failure: the Framingham study,” Journal of the American College of Cardiology, vol. 22, no. 4, pp. 6A–13A, 1993. View at Scopus
  16. R. Dhingra, H. D. Sesso, S. Kenchaiah, and J. M. Gaziano, “Differential effects of lipids on the risk of heart failure and coronary heart disease: the Physicians' health study,” American Heart Journal, vol. 155, no. 5, pp. 869–875, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Butler, A. Kalogeropoulos, V. Georgiopoulou et al., “Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 29, no. 7, pp. 1144–1149, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. L. C. van Vark, I. Kardys, G. S. Bleumink et al., “Lipoprotein-associated phospholipase A2 activity and risk of heart failure: the Rotterdam study,” European Heart Journal, vol. 27, no. 19, pp. 2346–2352, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. W. H. W. Tang, R. Katz, M. L. Brennan et al., “Usefulness of myeloperoxidase levels in healthy elderly subjects to predict risk of developing heart failure,” American Journal of Cardiology, vol. 103, no. 9, pp. 1269–1274, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. P. D. Home, S. J. Pocock, H. Beck-Nielsen et al., “Rosiglitazone evaluated for cardiovascular outcomes—an interim analysis,” The New England Journal of Medicine, vol. 357, no. 1, pp. 28–38, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Hippisley-Cox, C. Coupland, Y. Vinogradova, J. Robson, M. May, and P. Brindle, “Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study,” British Medical Journal, vol. 335, no. 7611, pp. 136–141, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. E. O'Meara, T. Clayton, M. B. McEntegart et al., “Sex differences in clinical characteristics and prognosis in a broad spectrum of patients with heart failure—results of the Candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) program,” Circulation, vol. 115, no. 24, pp. 3111–3120, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. J. H. Ware, “The limitations of risk factors as prognostic tools,” The New England Journal of Medicine, vol. 355, no. 25, pp. 2615–2617, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. P. W. F. Wilson, R. B. D'Agostino, D. Levy, A. M. Belanger, H. Silbershatz, and W. B. Kannel, “Prediction of coronary heart disease using risk factor categories,” Circulation, vol. 97, no. 18, pp. 1837–1847, 1998. View at Scopus
  25. J. S. Gottdiener, A. M. Arnold, G. P. Aurigemma et al., “Predictors of congestive heart failure in the elderly: the cardiovascular health study,” Journal of the American College of Cardiology, vol. 35, no. 6, pp. 1628–1637, 2000. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Eriksson, K. Svardsudd, B. Larsson et al., “Risk factors for heart failure in the general population: the study of men born in 1913,” European Heart Journal, vol. 10, no. 7, pp. 647–656, 1989. View at Scopus
  27. Y. T. Chen, V. Vaccarino, C. S. Williams, J. Butler, L. F. Berkman, and H. M. Krumholz, “Risk factors for heart failure in the elderly: a prospective community-based study,” American Journal of Medicine, vol. 106, no. 6, pp. 605–612, 1999. View at Publisher · View at Google Scholar · View at Scopus
  28. W. B. Kannel, R. B. D'Agostino, H. Silbershatz, A. J. Belanger, P. W. F. Wilson, and D. Levy, “Profile for estimating risk of heart failure,” Archives of Internal Medicine, vol. 159, no. 11, pp. 1197–1204, 1999. View at Publisher · View at Google Scholar · View at Scopus
  29. J. S. Gottdiener, D. J. Reda, D. W. Williams, and B. J. Materson, “Left atrial size in hypertensive men: influence of obesity, race and age,” Journal of the American College of Cardiology, vol. 29, no. 3, pp. 651–658, 1997. View at Publisher · View at Google Scholar · View at Scopus
  30. E. B. Levitan, A. Wolk, and M. A. Mittleman, “Consistency with the DASH diet and incidence of heart failure,” Archives of Internal Medicine, vol. 169, no. 9, pp. 851–857, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. L. Wilhelmsen, A. Rosengren, H. Eriksson, and G. Lappas, “Heart failure in the general population of men—morbidity, risk factors and prognosis,” Journal of Internal Medicine, vol. 249, no. 3, pp. 253–261, 2001. View at Publisher · View at Google Scholar · View at Scopus
  32. K. Bibbins-Domingo, F. Lin, E. Vittinghoff et al., “Predictors of heart failure among women with coronary disease,” Circulation, vol. 110, no. 11, pp. 1424–1430, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. A. A. Carr, P. R. Kowey, R. B. Devereux et al., “Hospitalizations for new heart failure among subjects with diabetes mellitus in the RENAAL and LIFE studies,” American Journal of Cardiology, vol. 96, no. 11, pp. 1530–1536, 2005. View at Publisher · View at Google Scholar · View at Scopus
  34. B. Butler, A. Kalogeropoulos, V. Georgiopoulou et al., “Incident heart failure prediction in the elderly: the health ABC heart failure score,” Circulation. Heart Failure, vol. 1, no. 2, pp. 125–133, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. A. P. Kalogeropoulos, V. V. Georgiopoulou, T. B. Harris et al., “Prediction of incident heart failure in the elderly: validation of the health abc hf model in the cardiovascular health study,” in Proceedings of the 58th Annual Scientific Session of the American-College-of-Cardiology, p. A165, 2009.
  36. P. A. McKee, W. P. Castelli, P. M. McNamara, and W. B. Kannel, “The natural history of congestive heart failure: the Framingham study,” The New England Journal of Medicine, vol. 285, no. 26, pp. 1441–1446, 1971. View at Scopus
  37. B. M. Psaty, L. H. Kuller, D. Bild et al., “Methods of assessing prevalent cardiovascular disease in the cardiovascular health study,” Annals of Epidemiology, vol. 5, no. 4, pp. 270–277, 1995. View at Publisher · View at Google Scholar · View at Scopus
  38. G. D. Schellenbaum, T. D. Rea, S. R. Heckbert et al., “Survival associated with two sets of diagnostic criteria for congestive heart failure,” American Journal of Epidemiology, vol. 160, no. 7, pp. 628–635, 2004. View at Publisher · View at Google Scholar · View at Scopus
  39. G. D. Schellenbaum, S. R. Heckbert, N. L. Smith et al., “Congestive heart failure incidence and prognosis: case identification using central adjudication versus hospital discharge diagnoses,” Annals of Epidemiology, vol. 16, no. 2, pp. 115–122, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. W. J. Paulus, C. Tschöpe, J. E. Sanderson et al., “How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the heart failure and echocardiography associations of the European society of cardiology,” European Heart Journal, vol. 28, no. 20, pp. 2539–2550, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. F. Zannad, W. G. Stough, B. Pitt et al., “Heart failure as an endpoint in heart failure and non-heart failure cardiovascular clinical trials: the need for a consensus definition,” European Heart Journal, vol. 29, no. 3, pp. 413–421, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. M. J. Stampfer, F. B. Hu, J. E. Manson, E. B. Rimm, and W. C. Willett, “Primary prevention of coronary heart disease in women through diet and lifestyle,” The New England Journal of Medicine, vol. 343, no. 1, pp. 16–22, 2000. View at Publisher · View at Google Scholar · View at Scopus
  43. P. S. Yusuf, S. Hawken, S. Ôunpuu et al., “Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study,” The Lancet, vol. 364, no. 9438, pp. 937–952, 2004. View at Publisher · View at Google Scholar · View at Scopus
  44. W. C. Knowler, E. Barrett-Connor, S. E. Fowler et al., “Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin,” The New England Journal of Medicine, vol. 346, no. 6, pp. 393–403, 2002. View at Publisher · View at Google Scholar · View at Scopus
  45. L. J. Appel, T. J. Moore, E. Obarzanek et al., “A clinical trial of the effects of dietary patterns on blood pressure,” The New England Journal of Medicine, vol. 336, no. 16, pp. 1117–1124, 1997. View at Scopus
  46. L. Djoussé, J. A. Driver, and J. M. Gaziano, “Relation between modifiable lifestyle factors and lifetime risk of heart failure,” The Journal of the American Medical Association, vol. 302, no. 4, pp. 394–400, 2009. View at Publisher · View at Google Scholar · View at Scopus
  47. S. Johansson, M. A. Wallander, A. Ruigómez, and L. A. García Rodríguez, “Incidence of newly diagnosed heart failure in UK general practice,” European Journal of Heart Failure, vol. 3, no. 2, pp. 225–231, 2001. View at Publisher · View at Google Scholar · View at Scopus
  48. S. Kenchaiah, H. D. Sesso, and J. M. Gaziano, “Body mass index and vigorous physical activity and the risk of heart failure among men,” Circulation, vol. 119, no. 1, pp. 44–52, 2009. View at Publisher · View at Google Scholar · View at Scopus
  49. C. Spies, R. Farzaneh-Far, B. Na, A. Kanaya, N. B. Schiller, and M. A. Whooley, “Relation of obesity to heart failure hospitalization and cardiovascular events in persons with stable coronary heart disease (from the heart and soul study),” American Journal of Cardiology, vol. 104, no. 7, pp. 883–889, 2009. View at Publisher · View at Google Scholar · View at Scopus
  50. B. J. Nicklas, M. Cesari, B. W. J. H. Penninx et al., “Abdominal obesity is an independent risk factor for chronic heart failure in older people,” Journal of the American Geriatrics Society, vol. 54, no. 3, pp. 413–420, 2006. View at Publisher · View at Google Scholar · View at Scopus
  51. S. Kenchaiah, J. M. Gaziano, and R. S. Vasan, “Impact of obesity on the risk of heart failure and survival after the onset of heart failure,” Medical Clinics of North America, vol. 88, no. 5, pp. 1273–1294, 2004. View at Publisher · View at Google Scholar · View at Scopus
  52. R. S. Vasan, “Cardiac function and obesity,” Heart, vol. 89, no. 10, pp. 1127–1129, 2003. View at Scopus
  53. S. S. Anand, S. Islam, A. Rosengren et al., “Risk factors for myocardial infarction in women and men: insights from the INTERHEART study,” European Heart Journal, vol. 29, no. 7, pp. 932–940, 2008. View at Publisher · View at Google Scholar · View at Scopus
  54. S. F. Quan and B. J. Gersh, “Cardiovascular consequences of sleep-disordered breathing: past, present and future: report of a workshop from the national center on sleep disorders research and the national heart, lung, and blood institute,” Circulation, vol. 109, no. 8, pp. 951–957, 2004. View at Publisher · View at Google Scholar · View at Scopus
  55. C. Wong and T. H. Marwick, “Alterations in myocardial characteristics associated with obesity: Detection, mechanisms, and implications,” Trends in Cardiovascular Medicine, vol. 17, no. 1, pp. 1–5, 2007. View at Publisher · View at Google Scholar · View at Scopus
  56. S. W. MacMahon, D. E. L. Wilcken, and G. J. Macdonald, “The effect of weight reduction on left ventricular mass. A randomized controlled trial in young, overweight hypertensive patients,” The New England Journal of Medicine, vol. 314, no. 6, pp. 334–339, 1986. View at Scopus
  57. J. E. Manson, P. Greenland, A. Z. LaCroix et al., “Walking compared with vigorous exercise for the prevention of cardiovascular events in women,” The New England Journal of Medicine, vol. 347, no. 10, pp. 716–725, 2002. View at Publisher · View at Google Scholar · View at Scopus
  58. N. L. Chase, X. Sui, D. C. Lee, and S. N. Blair, “The association of cardiorespiratory fitness and physical activity with incidence of hypertension in men,” American Journal of Hypertension, vol. 22, no. 4, pp. 417–424, 2009. View at Publisher · View at Google Scholar · View at Scopus
  59. F. B. Hu, T. Y. Li, G. A. Colditz, W. C. Willett, and J. E. Manson, “Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women,” The Journal of the American Medical Association, vol. 289, no. 14, pp. 1785–1791, 2003. View at Publisher · View at Google Scholar · View at Scopus
  60. M. T. Hamilton, D. G. Hamilton, and T. W. Zderic, “Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation,” Exercise and Sport Sciences Reviews, vol. 32, no. 4, pp. 161–166, 2004. View at Scopus
  61. T. M. Manini, J. E. Everhart, K. V. Patel et al., “Daily activity energy expenditure and mortality among older adults,” The Journal of the American Medical Association, vol. 296, no. 2, pp. 171–179, 2006. View at Publisher · View at Google Scholar · View at Scopus
  62. M. H. Murphy, S. N. Blair, and E. M. Murtagh, “Accumulated versus continuous exercise for health benefit: a review of empirical studies,” Sports Medicine, vol. 39, no. 1, pp. 29–43, 2009. View at Publisher · View at Google Scholar · View at Scopus
  63. W. E. Kraus, J. A. Houmard, B. D. Duscha et al., “Effects of the amount and intensity of exercise on plasma lipoproteins,” The New England Journal of Medicine, vol. 347, no. 19, pp. 1483–1492, 2002. View at Publisher · View at Google Scholar · View at Scopus
  64. V. A. Cornelissen and R. H. Fagard, “Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors,” Hypertension, vol. 46, no. 4, pp. 667–675, 2005. View at Publisher · View at Google Scholar · View at Scopus
  65. C. Kasapis and P. D. Thompson, “The effects of physical activity on serum C-reactive protein and inflammatory markers: a systematic review,” Journal of the American College of Cardiology, vol. 45, no. 10, pp. 1563–1569, 2005. View at Publisher · View at Google Scholar · View at Scopus
  66. W. L. Haskell, I. M. Lee, R. R. Pate et al., “Physical activity and public health: updated recommendation for adults from the American college of sports medicine and the American heart association,” Circulation, vol. 116, no. 9, pp. 1081–1093, 2007. View at Publisher · View at Google Scholar · View at Scopus
  67. M. Hamer and Y. Chida, “Walking and primary prevention: a meta-analysis of prospective cohort studies,” British Journal of Sports Medicine, vol. 42, no. 4, pp. 238–243, 2008. View at Publisher · View at Google Scholar · View at Scopus
  68. A. M. Lazarević, S. Nakatani, A. N. Nešković et al., “Early changes in left ventricular function in chronic asymptomatic alcoholics: relation to the duration of heavy drinking,” Journal of the American College of Cardiology, vol. 35, no. 6, pp. 1599–1606, 2000. View at Publisher · View at Google Scholar · View at Scopus
  69. C. L. Bryson, K. J. Mukamal, M. A. Mittleman et al., “The association of alcohol consumption and incident heart failure: the cardiovascular health study,” Journal of the American College of Cardiology, vol. 48, no. 2, pp. 305–311, 2006. View at Publisher · View at Google Scholar · View at Scopus
  70. C. R. Walsh, M. G. Larson, J. C. Evans et al., “Alcohol consumption and risk for congestive heart failure in the Framingham heart study,” Annals of Internal Medicine, vol. 136, no. 3, pp. 181–191, 2002. View at Scopus
  71. A. L. Klatsky, D. Chartier, N. Udaltsova et al., “Alcohol drinking and risk of hospitalization for heart failure with and without associated coronary artery disease,” American Journal of Cardiology, vol. 96, no. 3, pp. 346–351, 2005. View at Publisher · View at Google Scholar · View at Scopus
  72. L. Djoussé and J. M. Gaziano, “Alcohol consumption and heart failure in hypertensive us male physicians,” American Journal of Cardiology, vol. 102, no. 5, pp. 593–597, 2008. View at Publisher · View at Google Scholar · View at Scopus
  73. K. M. Conigrave, B. F. Hu, C. A. Camargo Jr., M. J. Stampfer, W. C. Willett, and E. B. Rimm, “A prospective study of drinking patterns in relation to risk of type 2 diabetes among men,” Diabetes, vol. 50, no. 10, pp. 2390–2395, 2001. View at Scopus
  74. J. M. Gaziano, J. E. Buring, J. L. Breslow et al., “Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction,” The New England Journal of Medicine, vol. 329, no. 25, pp. 1829–1834, 1993. View at Publisher · View at Google Scholar · View at Scopus
  75. L. Djoussé and J. M. Gaziano, “Breakfast cereals and risk of heart failure in the Physicians' health study I,” Archives of Internal Medicine, vol. 167, no. 19, pp. 2080–2085, 2007. View at Publisher · View at Google Scholar · View at Scopus
  76. L. Djoussé and J. M. Gaziano, “Egg consumption and risk of heart failure in the Physicians' health study,” Circulation, vol. 117, no. 4, pp. 512–516, 2008. View at Publisher · View at Google Scholar · View at Scopus
  77. D. Mozaffarian, C. L. Bryson, R. N. Lemaitre, G. L. Burke, and D. S. Siscovick, “Fish intake and risk of incident heart failure,” Journal of the American College of Cardiology, vol. 45, no. 12, pp. 2015–2021, 2005. View at Publisher · View at Google Scholar · View at Scopus
  78. J. He, L. G. Ogden, L. A. Bazzano, S. Vupputuri, C. Loria, and P. K. Whelton, “Dietary sodium intake and incidence of congestive heart failure in overweight US men and women: first national health and nutrition examination survey epidemiologic follow-up study,” Archives of Internal Medicine, vol. 162, no. 14, pp. 1619–1624, 2002. View at Publisher · View at Google Scholar · View at Scopus
  79. L. Djoussé, T. Rudich, and J. M. Gaziano, “Nut consumption and risk of heart failure in the Physicians' health study I,” American Journal of Clinical Nutrition, vol. 88, no. 4, pp. 930–933, 2008. View at Scopus
  80. A. J. Chicco, G. C. Sparagna, S. A. McCune et al., “Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets,” Hypertension, vol. 52, no. 3, pp. 549–555, 2008. View at Publisher · View at Google Scholar · View at Scopus
  81. I. C. Okere, D. J. Chess, T. A. McElfresh et al., “High-fat diet prevents cardiac hypertrophy and improves contractile function in the hypertensive Dahl salt-sensitive rat,” Clinical and Experimental Pharmacology and Physiology, vol. 32, no. 10, pp. 825–831, 2005. View at Publisher · View at Google Scholar · View at Scopus
  82. N. Sharma, I. C. Okere, M. K. Duda et al., “High fructose diet increases mortality in hypertensive rats compared to a complex carbohydrate or high fat diet,” American Journal of Hypertension, vol. 20, no. 4, pp. 403–409, 2007. View at Publisher · View at Google Scholar · View at Scopus
  83. F. J. He and G. A. MacGregor, “Salt, blood pressure and cardiovascular disease,” Current Opinion in Cardiology, vol. 22, no. 4, pp. 298–305, 2007. View at Publisher · View at Google Scholar · View at Scopus
  84. F. M. Sacks, L. P. Svetkey, W. M. Vollmer et al., “Effects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension (dash) diet,” The New England Journal of Medicine, vol. 344, no. 1, pp. 3–10, 2001. View at Publisher · View at Google Scholar · View at Scopus
  85. T. F. T. Antonios and G. A. MacGregor, “Salt—more adverse effects,” The Lancet, vol. 348, no. 9022, pp. 250–251, 1996. View at Publisher · View at Google Scholar · View at Scopus
  86. P. A. Swift, N. D. Markandu, G. A. Sagnella, F. J. He, and G. A. MacGregor, “Modest salt reduction reduces blood pressure and urine protein excretion in black hypertensives: a randomized control trial,” Hypertension, vol. 46, no. 2, pp. 308–312, 2005. View at Publisher · View at Google Scholar · View at Scopus
  87. N. Suskin, T. Sheth, A. Negassa, and S. Yusuf, “Relationship of current and past smoking to mortality and morbidity in patients with left ventricular dysfunction,” Journal of the American College of Cardiology, vol. 37, no. 6, pp. 1677–1682, 2001. View at Publisher · View at Google Scholar
  88. K. K. Teo, S. Ounpuu, S. Hawken et al., “Tobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case-control study,” The Lancet, vol. 368, no. 9536, pp. 647–658, 2006. View at Publisher · View at Google Scholar · View at Scopus
  89. M. I. Gembala, F. Ghanem, C. A. Mann, and V. L. Sorrell, “Acute changes in left ventricular diastolic function: cigarette smoking versus nicotine gum,” Clinical Cardiology, vol. 29, no. 2, pp. 61–64, 2006. View at Scopus
  90. W. C. Willett, A. Green, M. J. Stampfer et al., “Relative and absolute excess risks of coronary heart disease among women who smoke cigarettes,” The New England Journal of Medicine, vol. 317, no. 21, pp. 1303–1309, 1987. View at Scopus
  91. D. J. Moliterno, J. E. Willard, R. A. Lange et al., “Coronary-artery vasoconstriction induced by cocaine, cigarette smoking, or both,” The New England Journal of Medicine, vol. 330, no. 7, pp. 454–459, 1994. View at Publisher · View at Google Scholar · View at Scopus
  92. J. D. Morrow, B. Frei, A. W. Longmire et al., “Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers—smoking as a cause of oxidative damage,” The New England Journal of Medicine, vol. 332, no. 18, pp. 1198–1203, 1995. View at Publisher · View at Google Scholar · View at Scopus
  93. S. S. Ahmed, C. B. Moschos, and M. M. Lyons, “Cardiovascular effects of long term cigarette smoking and nicotine administration,” American Journal of Cardiology, vol. 37, no. 1, pp. 33–40, 1976. View at Scopus
  94. A. Bye, S. Sørhaug, M. Ceci et al., “Carbon monoxide levels experienced by heavy smokers impair aerobic capacity and cardiac contractility and induce pathological hypertrophy,” Inhalation Toxicology, vol. 20, no. 7, pp. 635–646, 2008. View at Publisher · View at Google Scholar · View at Scopus
  95. S. R. Heckbert, W. Post, G. D. N. Pearson et al., “Traditional cardiovascular risk factors in relation to left ventricular mass, volume, and systolic function by cardiac magnetic resonance imaging: the multiethnic study of atherosclerosis,” Journal of the American College of Cardiology, vol. 48, no. 11, pp. 2285–2292, 2006. View at Publisher · View at Google Scholar · View at Scopus
  96. B. Lichodziejewska, K. Kurnicka, K. Grudzka, J. Małysz, M. Ciurzyński, and D. Liszewska-Pfejfer, “Chronic and acute effects of smoking on left and right ventricular relaxation in young healthy smokers,” Chest, vol. 131, no. 4, pp. 1142–1148, 2007. View at Publisher · View at Google Scholar · View at Scopus
  97. S. A. Kenfield, M. J. Stampfer, B. A. Rosner, and G. A. Colditz, “Smoking and smoking cessation in relation to mortality in women,” The Journal of the American Medical Association, vol. 299, no. 17, pp. 2037–2047, 2008. View at Publisher · View at Google Scholar · View at Scopus
  98. S. S. Franklin, M. J. Jacobs, N. D. Wong, G. J. L'Italien, and P. Lapuerta, “Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on national health and nutrition examination survey (NHANES) III,” Hypertension, vol. 37, no. 3, pp. 869–874, 2001. View at Scopus
  99. S. S. Franklin, M. G. Larson, S. A. Khan et al., “Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham heart study,” Circulation, vol. 103, no. 9, pp. 1245–1249, 2001. View at Scopus
  100. J. B. Kostis, B. R. Davis, J. Cutler et al., “Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension,” The Journal of the American Medical Association, vol. 278, no. 3, pp. 212–216, 1997. View at Scopus
  101. D. Levy, M. G. Larson, R. S. Vasan, W. B. Kannel, and K. K. L. Ho, “The progression from hypertension to congestive heart failure,” The Journal of the American Medical Association, vol. 275, no. 20, pp. 1557–1562, 1996. View at Publisher · View at Google Scholar · View at Scopus
  102. D. M. Lloyd-Jones, M. G. Larson, E. P. Leip et al., “Lifetime risk for developing congestive heart failure: the Framingham heart study,” Circulation, vol. 106, no. 24, pp. 3068–3072, 2002. View at Publisher · View at Google Scholar · View at Scopus
  103. K. Wolf-Maier, R. S. Cooper, J. R. Banegas et al., “Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States,” The Journal of the American Medical Association, vol. 289, no. 18, pp. 2363–2369, 2003. View at Publisher · View at Google Scholar · View at Scopus
  104. P. M. Kearney, M. Whelton, K. Reynolds, P. Muntner, P. K. Whelton, and J. He, “Global burden of hypertension: analysis of worldwide data,” The Lancet, vol. 365, no. 9455, pp. 217–223, 2005. View at Publisher · View at Google Scholar · View at Scopus
  105. J. S. Drukteinis, M. J. Roman, R. R. Fabsitz et al., “Cardiac and systemic hemodynamic characteristics of hypertension and prehypertension in adolescents and young adults: the Strong heart study,” Circulation, vol. 115, no. 2, pp. 221–227, 2007. View at Publisher · View at Google Scholar · View at Scopus
  106. K. T. Weber, C. G. Brilla, S. E. Campbell, G. Zhou, L. Matsubara, and E. Guarda, “Pathologic hypertrophy with fibrosis: the structural basis for myocardial failure,” Blood Pressure, vol. 1, no. 2, pp. 75–85, 1992. View at Scopus
  107. R. S. Vasan and D. Levy, “The role of hypertension in the pathogenesis of heart failure: a clinical mechanistic overview,” Archives of Internal Medicine, vol. 156, no. 16, pp. 1789–1796, 1996. View at Publisher · View at Google Scholar · View at Scopus
  108. M. L. Marcus, D. G. Harrison, W. M. Chilian, et al., “Alterations in the coronary circulation in hypertrophied ventricles,” Circulation, vol. 75, no. 1, pp. I-19–I-25, 1987. View at Scopus
  109. S. E. Nolan, J. A. Mannisi, D. E. Bush, B. Healy, and H. F. Weisman, “Increased afterload aggravates infarct expansion after acute myocardial infarction,” Journal of the American College of Cardiology, vol. 12, no. 5, pp. 1318–1325, 1988. View at Scopus
  110. J. W. Wright, S. Mizutani, and J. W. Harding, “Pathways involved in the transition from hypertension to hypertrophy to heart failure. Treatment strategies,” Heart Failure Reviews, vol. 13, no. 3, pp. 367–375, 2008. View at Publisher · View at Google Scholar · View at Scopus
  111. J. W. Wright and J. W. Harding, “The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory,” Progress in Neurobiology, vol. 72, no. 4, pp. 263–293, 2004. View at Publisher · View at Google Scholar · View at Scopus
  112. P. R. Hebert, M. Moser, J. Mayer, R. J. Glynn, and C. H. Hennekens, “Recent evidence on drug therapy of mild to moderate hypertension and decreased risk of coronary heart disease,” Archives of Internal Medicine, vol. 153, no. 5, pp. 578–581, 1993. View at Publisher · View at Google Scholar · View at Scopus
  113. M. Moser and P. R. Hebert, “Prevention of disease progression, left ventricular hypertrophy and congestive heart failure in hypertension treatment trials,” Journal of the American College of Cardiology, vol. 27, no. 5, pp. 1214–1218, 1996. View at Publisher · View at Google Scholar · View at Scopus
  114. B. R. Davis, L. B. Piller, J. A. Cutler et al., “Role of diuretics in the prevention of heart failure: the antihypertensive and lipid-lowering treatment to prevent heart attack trial,” Circulation, vol. 113, no. 18, pp. 2201–2210, 2006. View at Publisher · View at Google Scholar · View at Scopus
  115. L. M. H. Wing, C. M. Reid, P. Ryan et al., “A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly,” The New England Journal of Medicine, vol. 348, no. 7, pp. 583–592, 2003. View at Publisher · View at Google Scholar · View at Scopus
  116. A. U. Klingbeil, M. Schneider, P. Martus, F. H. Messerli, and R. E. Schmieder, “A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension,” American Journal of Medicine, vol. 115, no. 1, pp. 41–46, 2003. View at Publisher · View at Google Scholar · View at Scopus
  117. K. Malmqvist, T. Kahan, M. Edner et al., “Regression of left ventricular hypertrophy in human hypertension with irbesartan,” Journal of Hypertension, vol. 19, no. 6, pp. 1167–1176, 2001. View at Publisher · View at Google Scholar · View at Scopus
  118. B. Dahlöf, R. B. Devereux, S. E. Kjeldsen et al., “Cardiovascular morbidity and mortality in the Losartan intervention for endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol,” The Lancet, vol. 359, no. 9311, pp. 995–1003, 2002. View at Publisher · View at Google Scholar · View at Scopus
  119. C. Cuspidi, M. L. Muiesan, L. Valagussa et al., “Comparative effects of candesartan and enalapril on left ventricular hypertrophy in patients with essential hypertension: the candesartan assessment in the treatment of cardiac hypertrophy (CATCH) study,” Journal of Hypertension, vol. 20, no. 11, pp. 2293–2300, 2002. View at Publisher · View at Google Scholar · View at Scopus
  120. P. Verdecchia, F. Angeli, C. Cavallini et al., “Blood pressure reduction and renin-angiotensin system inhibition for prevention of congestive heart failure: a meta-analysis,” European Heart Journal, vol. 30, no. 6, pp. 679–688, 2009. View at Publisher · View at Google Scholar · View at Scopus
  121. L. H. Lindholm, B. Carlberg, and O. Samuelsson, “Should β blockers remain first choice in the treatment of primary hypertension? A meta-analysis,” The Lancet, vol. 366, no. 9496, pp. 1545–1553, 2005. View at Publisher · View at Google Scholar · View at Scopus
  122. S. Bangalore, F. H. Messerli, J. B. Kostis, and C. J. Pepine, “Cardiovascular protection using β-blockers: a critical review of the evidence,” Journal of the American College of Cardiology, vol. 50, no. 7, pp. 563–572, 2007. View at Publisher · View at Google Scholar · View at Scopus
  123. S. Bangalore, D. Wild, S. Parkar, M. Kukin, and F. H. Messerli, “β-Blockers for primary prevention of heart failure in patients with hypertension. Insights from a meta-analysis,” Journal of the American College of Cardiology, vol. 52, no. 13, pp. 1062–1072, 2008. View at Publisher · View at Google Scholar · View at Scopus
  124. W. C. Cushman, C. E. Ford, J. A. Cutler et al., “Success and predictors of blood pressure control in diverse North American settings: the antihypertensive and lipid-lowering treatment to prevent heart attact trial (ALLHAT),” Journal of Clinical Hypertension, vol. 4, no. 6, pp. 393–404, 2002. View at Scopus
  125. P. Verdecchia, J. A. Staessen, F. Angeli et al., “Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial,” The Lancet, vol. 374, no. 9689, pp. 525–533, 2009. View at Publisher · View at Google Scholar · View at Scopus
  126. F. A. Masoudi and S. E. Inzucchi, “Diabetes mellitus and heart failure: epidemiology, mechanisms, and pharmacotherapy,” American Journal of Cardiology, vol. 99, no. 4, pp. 113–132, 2007. View at Publisher · View at Google Scholar · View at Scopus
  127. S. Boudina and E. D. Abel, “Diabetic cardiomyopathy revisited,” Circulation, vol. 115, no. 25, pp. 3213–3223, 2007. View at Publisher · View at Google Scholar · View at Scopus
  128. C. K. Choy, J. E. Rodgers, J. M. Nappi, and S. T. Haines, “Type 2 diabetes mellitus and heart failure,” Pharmacotherapy, vol. 28, no. 2, pp. 170–192, 2008. View at Publisher · View at Google Scholar · View at Scopus
  129. UK Prospective Diabetes Study (UKPDS) Group, “Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33),” The Lancet, vol. 352, no. 9131, pp. 837–853, 1998. View at Publisher · View at Google Scholar · View at Scopus
  130. S. E. Kahn, S. M. Haffner, M. A. Heise et al., “Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy,” The New England Journal of Medicine, vol. 355, no. 23, pp. 2427–2443, 2006. View at Publisher · View at Google Scholar · View at Scopus
  131. J. L. Chiasson, R. G. Josse, R. Gomis, M. Hanefeld, A. Karasik, and M. Laakso, “Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial,” The Journal of the American Medical Association, vol. 290, no. 4, pp. 486–494, 2003. View at Publisher · View at Google Scholar · View at Scopus
  132. UK Prospective Diabetes Study Group, “Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38,” British Medical Journal, vol. 317, no. 7160, p. 713, 1998.
  133. A. V. Chobanian, G. L. Bakris, H. R. Black et al., “The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report,” The Journal of the American Medical Association, vol. 289, no. 19, pp. 2560–2572, 2003. View at Publisher · View at Google Scholar · View at Scopus
  134. S. Yusuf, P. Sleight, J. Pogue et al., “Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients,” The New England Journal of Medicine, vol. 342, no. 3, pp. 145–153, 2000.
  135. Heart Outcomes Prevention Evaluation Study Investigators, “Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the hope study and micro-hope substudy,” The Lancet, vol. 355, no. 9200, pp. 253–259, 2000.
  136. J. Bosch, E. Lonn, J. Pogue, J. M. O. Arnold, G. R. Dagenais, and S. Yusuf, “Long-term effects of ramipril on cardiovascular events and on diabetes: results of the HOPE study extension,” Circulation, vol. 112, no. 9, pp. 1339–1346, 2005. View at Publisher · View at Google Scholar · View at Scopus
  137. B. M. Brenner, M. E. Cooper, D. de Zeeuw et al., “Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy,” The New England Journal of Medicine, vol. 345, no. 12, pp. 861–869, 2001. View at Publisher · View at Google Scholar · View at Scopus
  138. L. H. Lindholm, H. Ibsen, B. Dahlöf et al., “Cardiovascular morbidity and mortality in patients with diabetes in the Losartan intervention for endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol,” The Lancet, vol. 359, no. 9311, pp. 1004–1010, 2002. View at Publisher · View at Google Scholar · View at Scopus
  139. G. J. S. Cooper, A. A. Young, G. D. Gamble et al., “A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study,” Diabetologia, vol. 52, no. 4, pp. 715–722, 2009. View at Publisher · View at Google Scholar · View at Scopus
  140. G. J. S. Cooper, A. R. J. Phillips, S. Y. Choong et al., “Regeneration of the heart in diabetes by selective copper chelation,” Diabetes, vol. 53, no. 9, pp. 2501–2508, 2004. View at Publisher · View at Google Scholar · View at Scopus
  141. S. Setoguchi, R. J. Glynn, J. Avorn, M. A. Mittleman, R. Levin, and W. C. Winkelmayer, “Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysis,” Journal of the American College of Cardiology, vol. 51, no. 13, pp. 1247–1254, 2008. View at Publisher · View at Google Scholar · View at Scopus
  142. S. R. Tiyyagura and S. P. Pinney, “Left ventricular remodeling after myocardial infarction: past, present, and future,” Mount Sinai Journal of Medicine, vol. 73, no. 6, pp. 840–851, 2006. View at Scopus
  143. H. Ishii, T. Amano, T. Matsubara, and T. Murohara, “Pharmacological intervention for prevention of left ventricular remodeling and improving prognosis in myocardial infarction,” Circulation, vol. 118, no. 25, pp. 2710–2718, 2008. View at Publisher · View at Google Scholar · View at Scopus
  144. T. Baks, R. J. van Geuns, E. Biagini et al., “Effects of primary angioplasty for acute myocardial infarction on early and late infarct size and left ventricular wall characteristics,” Journal of the American College of Cardiology, vol. 47, no. 1, pp. 40–44, 2006. View at Publisher · View at Google Scholar · View at Scopus
  145. J. Vinten-Johansen, Z. Q. Zhao, A. J. Zatta, H. Kin, M. E. Halkos, and F. Kerendi, “Postconditioning: a new link in nature's armor against myocardial ischemia-reperfusion injury,” Basic Research in Cardiology, vol. 100, no. 4, pp. 295–310, 2005. View at Publisher · View at Google Scholar · View at Scopus
  146. L. Klein and M. Gheorghiade, “Coronary artery disease and prevention of heart failure,” Medical Clinics of North America, vol. 88, no. 5, pp. 1209–1235, 2004. View at Publisher · View at Google Scholar · View at Scopus
  147. A. Lerman and A. M. Zeiher, “Endothelial function: cardiac events,” Circulation, vol. 111, no. 3, pp. 363–368, 2005. View at Publisher · View at Google Scholar · View at Scopus
  148. F. Grigioni, D. Detaint, J. F. Avierinos, C. Scott, J. Tajik, and M. Enriquez-Sarano, “Contribution of ischemic mitral regurgitation to congestive heart failure after myocardial infarction,” Journal of the American College of Cardiology, vol. 45, no. 2, pp. 260–267, 2005. View at Publisher · View at Google Scholar · View at Scopus
  149. P. D. Henry, R. Schuchleib, J. Davis, E. S. Weiss, and B. E. Sobel, “Myocardial contracture and accumulation of mitochondrial calcium in ischemic rabbit heart,” The American Journal of Physiology, vol. 233, no. 6, pp. H677–H684, 1977. View at Scopus
  150. Y. Ito, J. Suko, and C. A. Chidsey, “Intracellular calcium and myocardial contractility. V. Calcium uptake of sarcoplasmic reticulum fractions in hypertrophied and failing rabbit hearts,” Journal of Molecular and Cellular Cardiology, vol. 6, no. 3, pp. 237–247, 1974. View at Scopus
  151. M. G. Sutton and N. Sharpe, “Left ventricular remodeling after myocardial infarction: pathophysiology and therapy,” Circulation, vol. 101, no. 25, pp. 2981–2988, 2000. View at Scopus
  152. G. Takemura, M. Nakagawa, H. Kanamori, S. Minatoguchi, and H. Fujiwara, “Benefits of reperfusion beyond infarct size limitation,” Cardiovascular Research, vol. 83, no. 2, pp. 269–276, 2009. View at Publisher · View at Google Scholar · View at Scopus
  153. E. Ambrosioni, C. Borghi, B. Magnani, and The Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study Investigators, “The effect of the angiotensin-converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction,” The New England Journal of Medicine, vol. 332, no. 2, pp. 80–85, 1995. View at Publisher · View at Google Scholar · View at Scopus
  154. K. M. Fox, “Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study),” The Lancet, vol. 362, no. 9386, pp. 782–788, 2003. View at Publisher · View at Google Scholar · View at Scopus
  155. M. A. Pfeffer, E. Braunwald, L. A. Moye et al., “Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction—results of the survival and ventricular enlargement trial,” The New England Journal of Medicine, vol. 327, no. 10, pp. 669–677, 1992. View at Scopus
  156. S. Yusuf, K. Teo, C. Anderson et al., “Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial,” The Lancet, vol. 372, no. 9644, pp. 1174–1183, 2008. View at Publisher · View at Google Scholar
  157. S. Yusuf, K. K. Teo, J. Pogue et al., “Telmisartan, ramipril, or both in patients at high risk for vascular events,” The New England Journal of Medicine, vol. 358, no. 15, pp. 1547–1559, 2008. View at Publisher · View at Google Scholar · View at Scopus
  158. E. M. Antman, M. Hand, P. W. Armstrong et al., “2007 Focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American college of cardiology/American heart association task force on practice guidelines,” Circulation, vol. 117, no. 2, pp. 296–329, 2008. View at Publisher · View at Google Scholar · View at Scopus
  159. W. S. Colucci, T. J. Kolias, K. F. Adams et al., “Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the REversal of VEntricular Remodeling with Toprol-XL (REVERT) trial,” Circulation, vol. 116, no. 1, pp. 49–56, 2007. View at Publisher · View at Google Scholar · View at Scopus
  160. B. Pitt, W. Remme, F. Zannad et al., “Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction,” The New England Journal of Medicine, vol. 348, no. 14, pp. 1309–1321, 2003. View at Publisher · View at Google Scholar · View at Scopus
  161. E. M. Antman, D. T. Anbe, P. W. Armstrong et al., “ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American college of cardiology/American heart association task force on practice guidelines (committee to revise the 1999 guidelines for the management of patients with acute myocardial infarction),” Circulation, vol. 110, no. 9, pp. e82–e292, 2004. View at Scopus
  162. H. Ishii, S. Ichimiya, M. Kanashiro et al., “Effects of receipt of chronic statin therapy before the onset of acute myocardial infarction: a retrospective study in patients undergoing primary percutaneous coronary intervention,” Clinical Therapeutics, vol. 28, no. 11, pp. 1812–1819, 2006. View at Publisher · View at Google Scholar · View at Scopus
  163. J. Kjekshus, T. Pedersen, A. G. Olsson, O. Faergeman, and K. Pyorala, “The effects of simvastatin on the incidence of heart failure in patients with coronary heart disease,” Journal of Cardiac Failure, vol. 3, no. 4, pp. 249–254, 1997.
  164. J. A. Udell and J. G. Ray, “Primary and secondary prevention of heart failure with statins,” Expert Review of Cardiovascular Therapy, vol. 4, no. 6, pp. 917–926, 2006. View at Publisher · View at Google Scholar · View at Scopus