Table 2: Plasma characteristics of wild-type (WT) and ob/ob (OB) mice receiving an AIN-93G diet (AIN) or a sterculic oil-supplemented diet (SO)1.
value2
WT AIN
WT SO
OB AIN
OB SO
d
g
d × g
Plasma lipids (mg/dL)
Triglyceride
117.1 ±12.0
87.5 ± 7.1
118.3 ± 3.1
122.2 ± 11.3
0.186
0.071
0.097
Total cholesterol
145.2 ± 6.6
136.5 ± 4.5
324.3 ± 7.6
290.0 ± 12.5
<0.05
<0.001
0.138
HDL-C
63.7 ± 8.1
68.7 ± 2.7
103.8 ± 4.2
92.0 ± 3.8
0.598
<0.001
0.165
LDL-C
21.2 ± 2.0
25.5 ± 3.2
72.8 ± 2.8
74.8 ± 3.5
0.301
<0.001
0.700
NEFA (mmol/L)
1.4 ± 0.1
1.2 ± 0.1
1.1 ± 0.1
1.2 ± 0.2
0.718
0.289
0.280
Plasma IL-6 (pg/mL)
96.9 ± 52.0
51.0 ± 15.8
67.8 ± 38.9
285.3 ± 52.0
0.454
0.047
0.138
1Data are presented as means ± SEM with = 5–7 per group.
2Data were analyzed by 2-way ANOVA with diet (SO or AIN) as one factor and the phenotype (WT or OB) as the second factor. -values are for an effect of diet (d), an effect of the genotype (g), or an interaction between the two (d × g).