Research Article
Immunoreactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Epithelial Malignant Tumors from Digestive System
Table 2
Immunorecognition of 14F7 Mab on some primary human tumors from digestive system.
| Histopathological type | No. cases (%) | Intensity range | Positive cells |
| Esophagus | | | | Upper portion | | | | Epidermoid Carcinoma | 2/11 (18,2) | +/+++ | 1/2 | Gastroesophageal junction | | | | Epidermoid Carcinoma | 1/2 (50) | +++ | 3 | Adenocarcinoma | 2/2 (100) | +++ | 3 | Stomach (adenocarcinoma) | | | | Well differentiated | 7/7 (100) | ++/+++ | 3 | Moderate differentiated | 2/2 (100) | +++ | 3 | Poorly differentiated | 3/3 (100) | ++/+++ | 3 | Large Intestine | | | | Adenocarcinoma | 12/12 (100) | +/+++ | 3 | Rectum | | | | Basaloid Carcinoma | 4/5 (80) | +/+++ | 3 | Epidermoid Carcinoma | 5/7 (71,4) | ++/+++ | 3 | Pancreas (adenocarcinoma) | | | | Well differentiated | 8/8 (100) | ++/+++ | 3 | Poorly differentiated | 3/3 (100) | +++ | 3 | Liver | | | | Hepatocellular carcinoma | 13/14 (92,8) | ++/+++ | 3 |
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Intensity: − negative, + weak, ++ moderate, +++ intense. Positive cells: 0 (negative to less than 5%), 1 (6–25%), 2 (26–50%), and 3 (more than 50%).
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