Research Article

Immunoreactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Epithelial Malignant Tumors from Digestive System

Table 2

Immunorecognition of 14F7 Mab on some primary human tumors from digestive system.

Histopathological typeNo. cases (%)Intensity rangePositive cells

Esophagus
Upper portion
 Epidermoid Carcinoma2/11 (18,2) +/+++1/2
Gastroesophageal junction
 Epidermoid Carcinoma1/2 (50) +++3
 Adenocarcinoma2/2 (100) +++3
Stomach (adenocarcinoma)
 Well differentiated 7/7 (100) ++/+++3
 Moderate differentiated 2/2 (100)+++3
 Poorly differentiated 3/3 (100) ++/+++3
Large Intestine
 Adenocarcinoma12/12 (100)+/+++3
Rectum
 Basaloid Carcinoma 4/5 (80)+/+++3
 Epidermoid Carcinoma 5/7 (71,4)++/+++3
Pancreas (adenocarcinoma)
 Well differentiated8/8 (100)++/+++3
 Poorly differentiated3/3 (100)+++3
Liver
 Hepatocellular carcinoma13/14 (92,8)++/+++3

Intensity: − negative, + weak, ++ moderate, +++ intense. Positive cells: 0 (negative to less than 5%), 1 (6–25%), 2 (26–50%), and 3 (more than 50%).