Research Article

In Vivo Effect of Arsenic Trioxide on Keap1-p62-Nrf2 Signaling Pathway in Mouse Liver: Expression of Antioxidant Responsive Element-Driven Genes Related to Glutathione Metabolism

Figure 4

(a) GSH content, (b) MDA production, (c) GST activity, (d) catalase activity in liver of different groups of mice exposed to different doses of As2O3. Groups II, III, IV, and V were compared with Group I. Values are expressed as mean ± SEM. *Values are statistically significant at ( ).
817693.fig.004a
(a)
817693.fig.004b
(b)
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(c)
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(d)