Table 1: Prognostic value of K-RAS mutations.

Author Total number of patients K-RAS mutations (%) Survival (value) Tsao et al. [24] 450 26.0 0.4 Schiller et al. [25] 184 24.0 0.38 Graziano et al. [26] 213 16.4 0.33 Keohavong et al. [27] 173 32 0.74 Lu et al. [28] 94 34 0.52 Slebos et al. [29] 69 27.5 0.002* Nelson et al. [30] 365 22.1 0.009* Fukuyama et al. [31] 159 6.9 <0.05* Huang et al. [32] 144 8.3 0.03* Miyake et al. [33] 187 8.0 0.037 Marks et al. [34] 296 17% NR

NR: not reported.*Statistically significant.