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ISRN Neurology
Volume 2012 (2012), Article ID 575168, 6 pages
doi:10.5402/2012/575168
Research Article

Complications of Intrathecal Baclofen Pump: Prevention and Cure

Yasser Awaad,1,2 Tamer Rizk,2 Iram Siddiqui,2 Norbert Roosen,3 Kelly Mcintosh,3 and G. Michael Waines4

1Pediatric Neurology and Movement Disorder Program, Oakwood Health System, Dearborn, MI, USA
2Department of Pediatric Neurology, National Neurosciences Institute, King Fahad Medical City, Riyadh 11393, Saudi Arabia
3Department of Neurosurgery, Henry Ford Health Systems, Detroit, MI, USA
4Operating Room Services, Oakwood Health System, Dearborn, MI, USA

Received 26 December 2011; Accepted 16 January 2012

Academic Editor: Y. Ersahin

Copyright © 2012 Yasser Awaad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. “Upper motor neuron control of the brainstem and spinal cord,” in Neuroscience, D. Purves, G. J. Augustine, D. Fitzpatrick, W. C. Hall, A.-S. LaMantia, J. O. McNamara, et al., Eds., pp. 414–415, Sinauer Publishers, Sunderland, Mass, USA, 3rd edition, 2004.
  2. “Lower motor neuron circuits and motor control,” in Neuroscience, D. Purves, G. J. Augustine, D. Fitzpatrick, W. C. Hall, A.-S. LaMantia, J. O. McNamara, et al., Eds., pp. 379–381, Sinauer Publishers, Sunderland, Mass, USA, 3rd edition, 2004.
  3. R. D. Penn and J. S. Kroin, “Intrathecal baclofen alleviates spinal cord spasticity,” Lancet, vol. 1, no. 8385, p. 1078, 1984. View at Scopus
  4. T. D. Sanger, M. R. Delgado, D. Gaebler-Spira, M. Hallett, and J. W. Mink, “Classification and definition of disorders causing hypertonia in childhood,” Pediatrics, vol. 111, no. 1, pp. e89–e97, 2003. View at Scopus
  5. C. B. Ivanhoe and T. A. Reistetter, “Spasticity: the misunderstood part of the upper motor neuron syndrome,” American Journal of Physical Medicine and Rehabilitation, vol. 83, no. 10, supplement, pp. S3–S9, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. B. Ashworth, “Preliminary trial of carisoprodol in multiple sclerosis,” The Practitioner, vol. 192, pp. 540–542, 1964. View at Scopus
  7. F. Biering-Sørensen, J. B. Nielsen, and K. Klinge, “Spasticity-assessment: a review,” Spinal Cord, vol. 44, no. 12, pp. 708–722, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. J. Whyte, K. M. Robinson, M. B. Glenn, and J. Whyte, Eds., The Practical Management of Spasticity in Children and Adults, Lea & Febiger, Philadelphia, Pa, USA, 1990.
  9. R. T. Katz and D. I. Campagnolo, “Pharmacologic management of spasticity.,” Physical Medicine and Rehabilitation, vol. 8, pp. 473–480, 1994.
  10. W. B. Van Winkle, “Calcium release from skeletal muscle sarcoplasmic reticulum: site of action of dantrolene sodium?” Science, vol. 193, no. 4258, pp. 1130–1131, 1976. View at Scopus
  11. J. T. Dall, R. L. Harmon, and C. M. Quinn, “Use of clonidine for treatment of spasticity arising from various forms of brain injury: a case series,” Brain Injury, vol. 10, no. 6, pp. 453–458, 1996. View at Scopus
  12. M. S. Kaplan, “Tizanidine: another tool in the management of spasticity,” Journal of Head Trauma Rehabilitation, vol. 12, no. 5, pp. 93–97, 1997. View at Scopus
  13. A. Badell, “The effect of medications that reduce spasticity in the management of spastic cerebral palsy,” Journal of Neurologic Rehabilitation, vol. 5, no. 1, supplement, pp. 13–14, 1991.
  14. R. R. Young, M. Emre, and P. W. Nance, “Current issues in spasticity management,” Neurologist, vol. 3, pp. 261–275, 1997.
  15. C. F. Terrence, G. H. Fromm, and M. S. Roussan, “Baclofen. Its effect on seizure frequency,” Archives of Neurology, vol. 40, no. 1, pp. 28–29, 1983. View at Scopus
  16. R. Gilmartin, D. Bruce, B. B. Storrs et al., “Intrathecal baclofen for management of spastic cerebral palsy: multicenter trial,” Journal of Child Neurology, vol. 15, no. 2, pp. 71–77, 2000. View at Scopus
  17. R. D. Penn, S. M. Savoy, D. Corcos et al., “Intrathecal baclofen for severe spinal spasticity,” New England Journal of Medicine, vol. 320, no. 23, pp. 1517–1521, 1989. View at Scopus
  18. Y. Awaad and T. Rizk, “Synergetic effect of intrathecal baclofen and deep brain stimulation in treating dystonia,” Journal of Pediatric Neurology, vol. 9, no. 2, pp. 221–225, 2011. View at Publisher · View at Google Scholar
  19. B. Sallerin and Y. Lazorthes, “Intrathecal baclofen. Experimental and pharmacokinetic studies,” Neurochirurgie, vol. 49, no. 2-3, pp. 271–275, 2003. View at Scopus