Clinical Study

The Effect of Fluoxetine on Progression in Progressive Multiple Sclerosis: A Double-Blind, Randomized, Placebo-Controlled Trial

Table 5

MRI outcomes (mean, sd).

Fluoxetine ( )Placebo ( ) value

Change in T2LL (mL)0.11 (0.3)0.31 (2.9)0.80
Change in WM volume (mL)−28.9 (68.7)−16.9 (62.6)0.59
Change in GM volume (mL)−37.7 (68.7)−18.7 (55.6)0.37

T2LL: T2 lesion load; WM: white matter; GM: grey matter.