- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Submit a Manuscript
- Table of Contents
Volume 2013 (2013), Article ID 375852, 5 pages
Noncoding RNAs in Neurodegenerative Diseases
1Department of Nutrition, Dietetics, and Hospitality Management, Auburn University, Auburn, AL 36849, USA
2Department of Physical Sciences, Auburn University at Montgomery, Montgomery, AL 36117, USA
3Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, AL 36849, USA
Received 27 February 2013; Accepted 10 April 2013
Academic Editors: A. Conti and T. Müller
Copyright © 2013 Shraddha D. Rege et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- I. A. Qureshi, J. S. Mattick, and M. F. Mehler, “Long non-coding RNAs in nervous system function and disease,” Brain Research, vol. 1338, pp. 20–35, 2010.
- J. S. Mattick, “The central role of RNA in human development and cognition,” FEBS Letters, vol. 585, no. 11, pp. 1600–1616, 2011.
- E. Salta and B. D. Strooper, “Non-coding RNAs with essential roles in neurodegenerative disorders,” The Lancet Neurology, vol. 11, no. 2, pp. 189–200, 2012.
- J. Kim, K. Inoue, J. Ishii et al., “A microRNA feedback circuit in midbrain dopamine neurons,” Science, vol. 317, no. 5842, pp. 1220–1224, 2007.
- M. D. Harraz, T. M. Dawson, and V. L. Dawson, “MicroRNAs in Parkinson's disease,” Journal of Chemical Neuroanatomy, vol. 42, no. 2, pp. 127–130, 2011.
- N. K. Liu and X. M. Xu, “MicroRNA in central nervous system trauma and degenerative disorders,” Physiological Genomics, vol. 43, no. 10, pp. 571–580, 2011.
- D. P. Bartel, “MicroRNAs: target recognition and regulatory functions,” Cell, vol. 136, no. 2, pp. 215–233, 2009.
- P. T. Nelson, W. X. Wang, and B. W. Rajeev, “MicroRNAs (miRNAs) in neurodegenerative diseases,” Brain Pathology, vol. 18, no. 1, pp. 130–138, 2008.
- S. Bian and T. Sun, “Functions of noncoding RNAs in neural development and neurological diseases,” Molecular Neurobiology, vol. 44, no. 3, pp. 359–373, 2011.
- P. Provost, “MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases,” Brain Research, vol. 1338, pp. 58–66, 2010.
- L. Du and A. Pertsemlidis, “Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation,” Journal of Molecular Cell Biology, vol. 3, no. 3, pp. 176–180, 2011.
- E. Vilardo, C. Barbato, M. Ciotti, C. Cogoni, and F. Ruberti, “MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons,” The Journal of Biological Chemistry, vol. 285, no. 24, pp. 18344–18351, 2010.
- G. Wang, J. M. van der Walt, G. Mayhew et al., “Variation in the miRNA-433 binding site of FGF20 confers risk for parkinson disease by overexpression of α-synuclein,” American Journal of Human Genetics, vol. 82, no. 2, pp. 283–289, 2008.
- S. S. Hebert, K. Horre, L. Nicolai et al., “Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression,” Proceedings of the National Academy of the Sciences of the United States of America, vol. 105, no. 17, pp. 6415–6420, 2008.
- W. X. Wang, Q. Huang, Y. Hu, A. J. Stromberg, and P. T. Nelson, “Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter,” Acta Neuropathologica, vol. 121, no. 2, pp. 193–205, 2011.
- V. Boissonneault, I. Plante, S. Rivest, and P. Provost, “MicroRNA-298 and microRNA-328 regulate expression of mouse β-amyloid precursor protein-converting enzyme 1,” The Journal of Biological Chemistry, vol. 284, no. 4, pp. 1971–1981, 2009.
- S. Massone, I. Vassallo, G. Fiorino et al., “17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease,” Neurobiology of Disease, vol. 41, no. 2, pp. 308–317, 2011.
- S. Massone, E. Ciarlo, S. Vella et al., “NDM29, a RNA polymerase III-dependent non-coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion,” Biochimica et Biophysica Acta, vol. 1823, no. 7, pp. 1170–1177, 2012.
- W. J. Lukiw, Y. Zhao, and G. C. Jian, “An NF-κB-sensitive micro RNA-146a-mediated inflammatory circuit in alzheimer disease and in stressed human brain cells,” The Journal of Biological Chemistry, vol. 283, no. 46, pp. 31315–31322, 2008.
- E. Junn, K. W. Lee, S. J. Byeong, T. W. Chan, J. Y. Im, and M. M. Mouradian, “Repression of α-synuclein expression and toxicity by microRNA-7,” Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 31, pp. 13052–13057, 2009.
- E. Doxakis, “Post-transcriptional regulation of α-synuclein expression by mir-7 and mir-153,” The Journal of Biological Chemistry, vol. 285, no. 17, pp. 12726–12734, 2010.
- S. Gehrke, Y. Imai, N. Sokol, and B. Lu, “Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression,” Nature, vol. 466, no. 7306, pp. 637–641, 2010.
- L. G. T. Morris, S. Veeriah, and T. A. Chan, “Genetic determinants at the interface of cancer and neurodegenerative disease,” Oncogene, vol. 29, no. 24, pp. 3453–3464, 2010.
- Y. Zhang and R. M. Friedlander, “Using non-coding small RNAs to develop therapies for Huntington's disease,” Gene Therapy, vol. 18, no. 12, pp. 1139–1149, 2011.
- R. Johnson and N. J. Buckley, “Gene dysregulation in Huntington's disease: REST, microRNAs and beyond,” Neuromolecular Medicine, vol. 11, no. 3, pp. 183–199, 2009.
- S. T. Lee, K. Chu, W. S. Im et al., “Altered microRNA regulation in Huntington's disease models,” Experimental Neurology, vol. 227, no. 1, pp. 172–179, 2011.
- E. Marti, L. Pantano, M. Banez-Coronel et al., “A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing,” Nucleic Acids Research, vol. 38, no. 20, pp. 7219–7235, 2010.
- C. Zuccato, A. Ciammola, D. Rigamonti et al., “Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease,” Science, vol. 293, no. 5529, pp. 493–498, 2001.
- N. Mellios, H. S. Huang, A. Grigorenko, E. Rogaev, and S. Akbarian, “A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex,” Human Molecular Genetics, vol. 17, no. 19, pp. 3030–3042, 2008.
- R. Johnson, C. Zuccato, N. D. Belyaev, D. J. Guest, E. Cattaneo, and N. J. Buckley, “A microRNA-based gene dysregulation pathway in Huntington's disease,” Neurobiology of Disease, vol. 29, no. 3, pp. 438–445, 2008.
- T. Nomura, M. Kimura, T. Horii et al., “MeCP2-dependent repression of an imprinted miR-184 released by depolarization,” Human Molecular Genetics, vol. 17, no. 8, pp. 1192–1199, 2008.
- C. Conaco, S. Otto, J. J. Han, and G. Mandel, “Reciprocal actions of REST and a microRNA promote neuronal identity,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 7, pp. 2422–2427, 2006.
- A. N. Packer, Y. Xing, S. Q. Harper, L. Jones, and B. L. Davidson, “The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease,” Journal of Neuroscience, vol. 28, no. 53, pp. 14341–14346, 2008.
- G. S. Mack, “MicroRNA gets down to business,” Nature Biotechnology, vol. 25, no. 6, pp. 631–638, 2007.
- T. A. Cooper, L. Wan, and G. Dreyfuss, “RNA and disease,” Cell, vol. 136, no. 4, pp. 777–793, 2009.
- L. L. Wang, Y. Huang, G. Wang, and S. D. Chen, “The potential role of microRNA-146 in Alzheimer's disease: biomarker or therapeutic?” Medical Hypotheses, vol. 78, no. 3, pp. 398–401, 2012.
- F. Modarressi, M. A. Faghihi, N. S. Patel, B. G. Sahagan, C. Wahlestedt, and M. A. Lopez-Toledano, “Knockdown of BACE1-AS Nonprotein-Coding Transcript modulates beta- amyloid related hippocampal neurogenesis,” International Journal of Alzheimer’s Disease, vol. 2011, Article ID 929042, 11 pages, 2011.
- J. P. Cogswell, J. Ward, I. A. Taylor et al., “Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways,” Journal of Alzheimer's Disease, vol. 14, no. 1, pp. 27–41, 2008.
- S. Q. Harper, P. D. Staber, X. He et al., “RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 16, pp. 5820–5825, 2005.
- P. Sazani and R. Kole, “Modulation of alternative splicing by antisense oligonucleotides,” Progress in Molecular and Subcellular Biology, vol. 31, pp. 217–239, 2003.
- W. Feng and Y. Feng, “MicroRNAs in neural cell development and brain diseases,” Science China Life Sciences, vol. 54, no. 12, pp. 1103–1112, 2011.