|Table 2: Comparative values of TTKG, Na and K balance before and after ondansetron show no effect on renal K wasting.|
|Values are presented as mean ± standard deviation.|
Student’s -test, paired, two-tailed, significance < 0.05.
Net balance = (intake − output)/weight (kg)/time (hr) of observation period.
PK: plasma potassium, mmol/L; UK: urine K, mmol/L; Posm: plasma osmolality, mmol/kg; Pald: plasma aldosterone, pmol/L (lower limit of detection 69 pmol/L); TTKG: transtubular potassium gradient; eGFR: estimated glomerular filtration rate (Schwartz ); Pna: plasma sodium, mmol/L; FENa: fractional excretion of sodium (%).
*5 subjects were not included in this analysis as they developed hypotonic urine relative to blood, invalidating the TTKG assumptions.