Journal Menu
- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Submit a Manuscript
- Table of Contents
ISRN Pediatrics
Volume 2012 (2012), Article ID 806920, 6 pages
doi:10.5402/2012/806920
Review Article
Component-Resolved Diagnosis in Pediatrics
Asthma and Allergy Clinic, Children’s Clinic Randers, Dytmærsken 9, 8900 Randers, Denmark
Received 5 June 2012; Accepted 28 June 2012
Academic Editors: M. Sánchez-Solís, K. Tokiwa, and D. D. Trevisanuto
Copyright © 2012 Ole D. Wolthers. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- J. Sastre, “Molecular diagnosis in allergy,” Clinical and Experimental Allergy, vol. 40, no. 10, pp. 1442–1460, 2010. View at Publisher · View at Google Scholar · View at Scopus
- M. P. Borres, M. Ebisawa, and P. A. Eigenmann, “Use of allergen components begins a new era in pediatric allergology,” Pediatric Allergy and Immunology, vol. 22, no. 5, pp. 454–461, 2011. View at Publisher · View at Google Scholar · View at Scopus
- M. Ferrer, M. L. Sanz, J. Sastre, et al., “Molecular diagnosis in allergologgy: application of the microarray technique,” Journal Allergology and Clinical Immunology, vol. 19, supplement 1, pp. 19–24, 2009.
- J. Lidholm, B. K. Ballmer-Weber, A. Mari, and S. Vieths, “Component-resolved diagnostics in food allergy,” Current Opinion in Allergy and Clinical Immunology, vol. 6, no. 3, pp. 234–240, 2006. View at Publisher · View at Google Scholar · View at Scopus
- A. E. Flinterman, E. van Hoffen, C. F. den Hartog Jager et al., “Children with peanut allergy recognize predominantly Ara h2 and Ara h6, which remains stable over time,” Clinical and Experimental Allergy, vol. 37, no. 8, pp. 1221–1228, 2007. View at Publisher · View at Google Scholar · View at Scopus
- R. A. McDermott, H. S. Porterfield, R. E. Mezayen et al., “Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation,” Clinical and Experimental Allergy, vol. 37, no. 5, pp. 752–763, 2007. View at Publisher · View at Google Scholar · View at Scopus
- D. Mittag, J. Akkerdaas, B. K. Ballmer-Weber et al., “Ara h 8, a Bet v 1-homologous allergen from peanut, is a major allergen in patients with combined birch pollen and peanut allergy,” Journal of Allergy and Clinical Immunology, vol. 114, no. 6, pp. 1410–1417, 2004. View at Publisher · View at Google Scholar · View at Scopus
- N. Nicolaou, C. Murray, D. Belgrave, M. Poorafshar, A. Simpson, and A. Custovic, “Quantification of specific IgE to whole peanut extract and peanut components in prediction of peanut allergy,” Journal of Allergy and Clinical Immunology, vol. 127, no. 3, pp. 684–685, 2011. View at Publisher · View at Google Scholar · View at Scopus
- A. Asarnoj, E. Östblom, S. Ahlstedt et al., “Reported symptoms to peanut between 4 and 8 years among children sensitized to peanut and birch pollen—results from the BAMSE birth cohort,” Allergy, vol. 65, no. 2, pp. 213–219, 2010. View at Publisher · View at Google Scholar · View at Scopus
- E. A. Pastorello, S. Vieths, V. Pravettoni et al., “Identification of hazelnut major allergens in sensitive patients with positive double-blind, placebo-controlled food challenge results,” Journal of Allergy and Clinical Immunology, vol. 109, no. 3, pp. 563–570, 2002. View at Publisher · View at Google Scholar · View at Scopus
- K. S. Hansen, B. K. Ballmer-Weber, J. Sastre et al., “Component-resolved in vitro diagnosis of hazelnut allergy in Europe,” Journal of Allergy and Clinical Immunology, vol. 123, no. 5, pp. 1134–e3, 2009. View at Publisher · View at Google Scholar · View at Scopus
- T. Komata, L. Söderström, M. P. Borres, H. Tachimoto, and M. Ebisawa, “Usefulness of wheat and soybean specific IgE antibody titers for the diagnosis of food allergy,” Allergology International, vol. 58, no. 4, pp. 599–603, 2009. View at Publisher · View at Google Scholar · View at Scopus
- K. Ito, M. Futamura, M. P. Borres et al., “IgE antibodies to ω-5 gliadin associate with immediate symptoms on oral wheat challenge in Japanese children,” Allergy, vol. 63, no. 11, pp. 1536–1542, 2008. View at Publisher · View at Google Scholar · View at Scopus
- F. Battais, F. Pineau, Y. Popineau et al., “Food allergy to wheat: identification of immunogloglin E and immunoglobulin G-binding proteins with sequential extracts and purified proteins from wheat flour,” Clinical and Experimental Allergy, vol. 33, no. 7, pp. 962–970, 2003. View at Publisher · View at Google Scholar · View at Scopus
- K. Ito, S. Sjölander, S. Sato et al., “IgE to Gly m 5 and Gly m 6 is associated with severe allergic reactions to soybean in Japanese children,” Journal of Allergy and Clinical Immunology, vol. 128, no. 3, pp. 673–675, 2011. View at Publisher · View at Google Scholar · View at Scopus
- T. Holzhauser, O. Wackermann, B. K. Ballmer-Weber et al., “Soybean (Glycine max) allergy in Europe: Gly m 5 (β-conglycinin) and Gly m 6 (glycinin) are potential diagnostic markers for severe allergic reactions to soy,” Journal of Allergy and Clinical Immunology, vol. 123, no. 2, pp. 452.e4–458.e4, 2009. View at Publisher · View at Google Scholar · View at Scopus
- H. J. Park, J. H. Kim, J. E. Kim, et al., “Diagnostic value of the serum-specific IgE ratio of ?-5 gliadin to wheat in adult patients with wheat-induced anaphylaxis,” International Archives of Allergy and Immunology, vol. 157, no. 2, pp. 147–150, 2011.
- P. Kosma, S. Sjölander, E. Landgren, M. P. Borres, and G. Hedlin, “Severe reactions after the intake of soy drink in birch pollen-allergic children sensitized to Gly m 4,” Acta Paediatrica, vol. 100, no. 2, pp. 305–307, 2011. View at Publisher · View at Google Scholar · View at Scopus
- A. H. Benhamou, J. C. Caubet, P. A. Eigenmann et al., “State of the art and new horizons in the diagnosis and management of egg allergy,” Allergy, vol. 65, no. 3, pp. 283–289, 2010. View at Publisher · View at Google Scholar · View at Scopus
- H. Ando, R. Movérare, Y. Kondo et al., “Utility of ovomucoid-specific IgE concentrations in predicting symptomatic egg allergy,” Journal of Allergy and Clinical Immunology, vol. 122, no. 3, pp. 583–588, 2008. View at Publisher · View at Google Scholar · View at Scopus
- H. Lemon-Mulé, H. A. Sampson, S. H. Sicherer, W. G. Shreffler, S. Noone, and A. Nowak-Wegrzyn, “Immunologic changes in children with egg allergy ingesting extensively heated egg,” Journal of Allergy and Clinical Immunology, vol. 122, no. 5, pp. 977.e1–983.e1, 2008. View at Publisher · View at Google Scholar · View at Scopus
- T. Boyano-Martínez, C. García-Ara, M. Pedrosa, J. M. Díaz-Pena, and S. Quirce, “Accidental allergic reactions in children allergic to cow's milk proteins,” Journal of Allergy and Clinical Immunology, vol. 123, no. 4, pp. 883–888, 2009. View at Publisher · View at Google Scholar · View at Scopus
- C. Constantin, S. Quirce, M. Poorafshar et al., “Micro-arrayed wheat seed and grass pollen allergens for component-resolved diagnosis,” Allergy, vol. 64, no. 7, pp. 1030–1037, 2009. View at Publisher · View at Google Scholar · View at Scopus
- C. Hejl, P. A. Wurtzen, J. Kleine-Tebbe, N. Johansen, L. Broge, and H. Ipsen, “Phleum pratense alone is sufficient for allergen-specific immunotherapy against allergy to Pooideae grass pollens,” Clinical and Experimental Allergy, vol. 39, no. 5, pp. 752–759, 2009. View at Publisher · View at Google Scholar · View at Scopus
- I. Swoboda, T. Twaroch, R. Valenta, and M. Grote, “Tree pollen allergens,” Clinical Allergy and Immunology, vol. 21, pp. 87–105, 2008. View at Scopus
- G. Menz, C. Dolecek, U. Schönheit-Kenn et al., “Serological and skin-test diagnosis of birch pollen allergy with recombinant Bet v I, the major birch pollen allergen,” Clinical and Experimental Allergy, vol. 26, no. 1, pp. 50–60, 1996. View at Publisher · View at Google Scholar · View at Scopus
- R. Movérare, K. Westritschnig, M. Svensson et al., “Different IgE reactivity profiles in birch pollen-sensitive patients from six European populations revealed by recombinant allergens: an imprint of local sensitization,” International Archives of Allergy and Immunology, vol. 128, no. 4, pp. 325–335, 2002. View at Scopus
- N. Mothes and R. Valenta, “Biology of tree pollen allergens,” Current Allergy and Asthma Reports, vol. 4, no. 5, pp. 384–390, 2004. View at Scopus
- A. Martínez, J. A. Asturias, J. Monteseirín et al., “The allergenic relevance of profilin (Ole e 2) from Olea europaea pollen,” Allergy, vol. 57, supplement 71, pp. 17–23, 2002. View at Scopus
- R. Valenta, B. Hayek, S. Seiberler et al., “Calcium-binding allergens: from plants to man,” International Archives of Allergy and Immunology, vol. 117, no. 3, pp. 160–166, 1998. View at Scopus
- G. Pittner, S. Vrtala, W. R. Thomas et al., “Component-resolved diagnosis of house-dust mite allergy with purified natural and recombinant mite allergens,” Clinical and Experimental Allergy, vol. 34, no. 4, pp. 597–603, 2004. View at Publisher · View at Google Scholar · View at Scopus
- J. Fernandes, A. Reshef, L. Patton, R. Ayuso, G. Reese, and S. B. Lehrer, “Immunoglobulin E antibody reactivity to the major shrimp allergen, tropomyosin, in unexposed Orthodox Jews,” Clinical and Experimental Allergy, vol. 33, no. 7, pp. 956–961, 2003. View at Publisher · View at Google Scholar · View at Scopus
- H. Grönlund, T. Saarne, G. Gafvelin, and M. van Hage, “The major cat allergen, fel d 1, in diagnosis and therapy,” International Archives of Allergy and Immunology, vol. 151, no. 4, pp. 265–274, 2010. View at Publisher · View at Google Scholar · View at Scopus
- C. Hilger, M. Kohnen, F. Grigioni, C. Lehners, and F. Hentges, “Allergic cross-reactions between cat and pig serum albumin. Study at the protein and DNA levels,” Allergy, vol. 52, no. 2, pp. 179–187, 1997. View at Scopus
- S. Saarelainen, A. Taivainen, M. Rytkönen-Nissinen et al., “Assessment of recombinant dog allergens Can f 1 and Can f 2 for the diagnosis of dog allergy,” Clinical and Experimental Allergy, vol. 34, no. 10, pp. 1576–1582, 2004. View at Publisher · View at Google Scholar · View at Scopus
- L. Mattsson, T. Lundgren, H. Everberg, H. Larsson, and J. Lidholm, “Prostatic kallikrein: a new major dog allergen,” Journal of Allergy and Clinical Immunology, vol. 123, no. 2, pp. 362.e3–368.e3, 2009. View at Publisher · View at Google Scholar · View at Scopus
- R. Cabanas, M. C. Lopez-Serrano, J. Carreira, et al., “Importance of albumin in cross-reactivity among cat, dog and horse allergens,” Journal of Investigational Allergology and Clinical Immunology, vol. 10, pp. 71–77, 2000.
- S. Saarelainen, M. Rytkönen-Nissinen, J. Rouvinen et al., “Animal-derived lipocalin allergens exhibit immunoglobulin E cross-reactivity,” Clinical and Experimental Allergy, vol. 38, no. 2, pp. 374–381, 2008. View at Publisher · View at Google Scholar · View at Scopus
- D. C. De Graaf, M. Aerts, E. Danneels, and B. Devreese, “Bee, wasp and ant venomics pave the way for a component-resolved diagnosis of sting allergy,” Journal of Proteomics, vol. 72, no. 2, pp. 145–154, 2009. View at Publisher · View at Google Scholar · View at Scopus
- B. M. Biló, F. Rueff, H. Mosbech et al., “Diagnosis of Hymenoptera venom allergy,” Allergy, vol. 60, no. 11, pp. 1339–1349, 2005. View at Publisher · View at Google Scholar · View at Scopus
- K. Skamstrup Hansen and L. K. Poulsen, “Component resolved testing for allergic sensitization,” Current Allergy and Asthma Reports, vol. 10, no. 5, pp. 340–348, 2010. View at Publisher · View at Google Scholar · View at Scopus
- O. D. Wolthers and M. Staberg, “A comparison of the usefulness of the multiple allergen simultaneous test-chemiluminescent assay as compared to the phadia immunocap IgE test panel system in children and adolescents.,” Recent Patents on Inflammation & Allergy Drug Discovery. In press.