Development and Validation of a HPLC and an UV Spectrophotometric Methods for Determination of Dexibuprofen in Pharmaceutical Preparations

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="7"><hr/></td></tr><tr><td align="left"></td><td align="center" colspan="2">HPLC</td><td align="center" colspan="2">UV</td><td align="center">HPLC</td><td align="center">UV</td></tr><tr><td align="left" rowspan="2">Drug</td><td align="center" colspan="2">Amount mg/tab</td><td align="center" colspan="2">Amount mg/tab</td><td align="center" colspan="2">% Recovery</td></tr><tr><td align="center">Labelled</td><td align="center">Found</td><td align="center">Labelled</td><td align="center">Found</td><td align="center"></td><td align="left"></td></tr><tr><td align="center" colspan="7"><hr/></td></tr><tr><td align="left"></td><td align="center">400</td><td align="center">385.23</td><td align="center">400</td><td align="center">378.89</td><td align="center">96.30</td><td align="center">95.89</td></tr><tr><td align="left">Dexibuprofen</td><td align="center">300</td><td align="center">291.98</td><td align="center">300</td><td align="center">285.67</td><td align="center">97.32</td><td align="center">93.12</td></tr><tr><td align="left"></td><td align="center">200</td><td align="center">189.83</td><td align="center">200</td><td align="center">185.42</td><td align="center">94.91</td><td align="center">92.05</td></tr><tr class="table-tr"><td colspan="7"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Results obtained for determination of dexibuprofen in SIBET marketed formulations.

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Table 4

Table 4: Development and Validation of a HPLC and an UV Spectrophotometric Methods for Determination of Dexibuprofen in Pharmaceutical Preparations 