Table 3:
Order of drug release of various formulations determined by the regression coefficients.
Formulation
**
r
2
4*
n
Zero order
First order
Higuchi
3*
Log
k
UF-3 gel
0.9961
0.8843
0.9792
0.7327
0.7574
UF-3
0.9742
0.7931
0.9534
0.8143
0.8304
Carbopol gel
0.8227
0.9964
0.9346
0.9923
0.9953
Plain drug
0.6081
0.9582
0.8687
1.2465
1.2314
∗∗
Coefficient of correlation,
3
∗
kinetic constant, and
4
∗
diffusional exponent indicative of the mechanism of drug release.