- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Submit a Manuscript
- Table of Contents
Volume 2012 (2012), Article ID 187208, 8 pages
The Effect of Tempol Administration on the Aortic Contractile Responses in Rat Preeclampsia Model
1Department of Pharmacology, Shiraz University of Medical Sciences, Shiraz 71348-53185, Iran
2Herbal Medicine Research Center, School of Medicine, Yasouj University of Medical Sciences, Yasouj, Iran
3Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Received 7 April 2012; Accepted 17 July 2012
Academic Editors: G. Biala, M. Brunner, and K. Cimanga
Copyright © 2012 Mohammad Sharif Talebianpoor and Hossein Mirkhani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- M. Noris, N. Perico, and G. Remuzzi, “Mechanisms of disease: pre-eclampsia,” Nature Clinical Practice. Nephrology, vol. 1, no. 2, pp. 98–114, 2005.
- M. Sedeek, J. S. Gilbert, B. B. Lamarca et al., “Role of reactive oxygen species in hypertension produced by reduced uterine perfusion in pregnant rats,” American Journal of Hypertension, vol. 21, no. 10, pp. 1152–1156, 2008.
- R. A. Khalil and J. P. Granger, “Vascular mechanisms of increased arterial pressure in preeclampsia: Lessons from animal models,” American Journal of Physiology—Regulatory Integrative and Comparative Physiology, vol. 283, no. 1, pp. R29–R45, 2002.
- E. Podjarny, G. Losonczy, and C. Baylis, “Animal models of preeclampsia,” Seminars in Nephrology, vol. 24, no. 6, pp. 596–606, 2004.
- H. M. Tanir, T. Sener, M. Inal, F. Akyuz, K. Uzuner, and E. Sivri, “Effect of quercetine and glutathione on the level of superoxide dismutase, catalase, malonyldialdehyde, blood pressure and neonatal outcome in a rat model of pre-eclampsia induced by NG-nitro-L-arginine-methyl ester,” European Journal of Obstetrics Gynecology and Reproductive Biology, vol. 118, no. 2, pp. 190–195, 2005.
- M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976.
- D. V. Hoyland and A. J. Taylor, “A review of the methodology of the 2-thiobarbituric acid test,” Food Chemistry, vol. 40, no. 3, pp. 271–291, 1991.
- J. S. Beckman and W. H. Koppenol, “Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly,” American Journal of Physiology—Cell Physiology, vol. 271, no. 5, pp. C1424–C1437, 1996.
- U. Simonsen, R. Rodriguez-Rodriguez, T. Dalsgaard, N. H. Buus, and E. Stankevicius, “Novel approaches to improving endothelium-dependent nitric oxide-mediated vasodilatation,” Pharmacological Reports, vol. 61, no. 1, pp. 105–115, 2009.
- C. Ma, Y. Zhuang, and Y. Xu, “The effect of inhibition of nitric oxide synthesis on vasoregulatory factors in pregnant rats,” Zhonghua Fu Chan Ke Za Zhi, vol. 34, no. 9, pp. 521–524, 1999.
- H. Tsukahara, M. Hiraoka, R. Kobata et al., “Increased oxidative stress in rats with chronic nitric oxide depletion: measurement of urinary 8-hydroxy-2′-deoxyguanosine excretion,” Redox Report, vol. 5, no. 1, pp. 23–28, 2000.
- J. Duarte, R. Jiménez, F. O'Valle et al., “Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats,” Journal of Hypertension, vol. 20, no. 9, pp. 1843–1854, 2002.
- Y. Ozawa, K. Hayashi, T. Kanda et al., “Impaired nitric oxide- and endothelium-derived hyperpolarizing factor-dependent dilation of renal afferent arteriole in Dahl salt-sensitive rats,” Nephrology, vol. 9, no. 5, pp. 272–277, 2004.
- X. Gao, S. Belmadani, A. Picchi et al., “Tumor necrosis factor-alpha induces endothelial dysfunction in Lepr(db) mice,” Circulation, vol. 115, no. 2, pp. 245–254, 2007.
- L. Xiang, J. Dearman, S. R. Abram, C. Carter, and R. L. Hester, “Insulin resistance and impaired functional vasodilation in obese Zucker rats,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 294, no. 4, pp. H1658–H1666, 2008.
- D. S. Hoffmann, C. J. Weydert, E. Lazartigues et al., “Chronic tempol prevents hypertension, proteinuria, and poor feto-placental outcomes in BPH/5 mouse model of preeclampsia,” Hypertension, vol. 51, no. 4, pp. 1058–1065, 2008.
- S. C. Preti, V. da Cunha, D. V. Vassallo, and I. Stefanon, “The superoxide dismutase mimetic, tempol, reduces the bioavailability of nitric oxide and does not alter L-NAME-induced hypertension in rats,” Basic and Clinical Pharmacology and Toxicology, vol. 97, no. 1, pp. 29–34, 2005.
- N. Ardanaz, W. H. Beierwaltes, and P. J. Pagano, “Distinct hydrogen peroxide-induced constriction in multiple mouse arteries: potential influence of vascular polarization,” Pharmacological Reports, vol. 60, no. 1, pp. 61–67, 2008.
- A. B. García-Redondo, A. M. Briones, A. E. Beltrán, M. J. Alonso, U. Simonsen, and M. Salaices, “Hypertension increases contractile responses to hydrogen peroxide in resistance arteries through increased thromboxane A2, Ca2+, and superoxide anion levels,” Journal of Pharmacology and Experimental Therapeutics, vol. 328, no. 1, pp. 19–27, 2009.
- Y. F. Chen, A. W. Cowley Jr., and A. P. Zou, “Increased H2O2 counteracts the vasodilator and natriuretic effects of superoxide dismutation by tempol in renal medulla,” American Journal of Physiology—Regulatory Integrative and Comparative Physiology, vol. 285, no. 4, pp. R827–R833, 2003.
- C. van Breemen, P. Aaronson, and R. Loutzenhiser, “Sodium-calcium interactions in mammalian smooth muscle,” Pharmacological Reviews, vol. 30, no. 2, pp. 167–208, 1978.
- E. Suematsu, M. Hirata, T. Hashimoto, and H. Kuriyama, “Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular store sites in skinned single cells of porcine coronary artery,” Biochemical and Biophysical Research Communications, vol. 120, no. 2, pp. 481–485, 1984.
- R. A. Khalil and C. van Breemen, “Mechanisms of calcium mobilization and homeostasis in vascular smooth muscle and their relevance to hypertension,” in Hypertension: Pathophysiology, Diagnosis Management, J. H. Laragh and B. M. Brenner, Eds., pp. 523–540, Raven Press, New York, NY, USA, 1995.
- Y. M. Park, M. Y. Park, Y. L. Suh, and J. B. Park, “NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats,” Biochemical and Biophysical Research Communications, vol. 313, no. 3, pp. 812–817, 2004.
- A. S. O. Adeagbo, I. G. Joshua, C. Falkner, and P. J. Matheson, “Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension,” European Journal of Pharmacology, vol. 481, no. 1, pp. 91–100, 2003.
- L. C. Kenny, P. N. Baker, D. A. Kendall, M. D. Randall, and W. R. Dunn, “Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsia,” Clinical Science, vol. 103, no. 1, pp. 67–73, 2002.