The actions of adult stem cells to achieve therapeutic value are carried out through two main pathways: (1) differentiation into new tissue and (2) stem cell released molecules (SRM). Up to 80% of the healing actions of stem cells have been seen to occur through the paracrine and autocrine actions of the SRM. The paracrine and autocrine actions of the SRM help to generate tissue, modulate the immune system, and regulate the stem cell niche.