Table 2: Median (interquartile interval) of the time and frequency domain indices of heart rate variability in HIV-infected patients (treated or not treated with HAART), diabetics, and controls.

HAART (%) Naïve Diabetes (%) Controls (%) Time Index R-R Interval (m/s) 903.1 (758.9–959.5) 908.1 (771.1–1007.5) 883.2 (755.0–933.3) 844.3 (797.1–914.8) 0.55 SDNN (m/s) 26.9 (34.2–64.3) 45.6 (33.0–72.5) 39.1 (25.5–42.7) 45.6 (32.3–62.3) 0.059 pNN50 (%) 3.1 (0.6–11.0) 5.4 (1.0–28.5) 3.4 (0.9–12.0) 7.7 (1.6–20.4) 0.32 r-MSSD (ms) 26.2 (18.5–48.8) 36.5 (25.4–69.2) 25.8 (17.8–40.3) 30.7 (219.2–43.7) 0.36 Low frequency spectral area (ms2) 45.8 (23.1–60.1) 42.2 (33.2–68.2) 25.8 (17.8–40.3) 60.3 (40.3–73.3) 0.06 High frequency spectral area (ms2) 46.2 (31.2–74.1) 47.5 (29.5–60.4) 50.1 (42.1–67.9) 29.5 (21.8–58.2) 0.06 Normalized low frequency area 46.1 (30.6–62.0) 39.9 (28.5–65.7) 42.9 (14.5–57.7) 67.5 (37.9–75.4) 0.04 Normalized high frequency area 45.3 (30.6–67.2) 49.7 (30.4–64.8) 53.5 (34.5–72.2) 27.0 (19.0–57.3) 0.03 LF/HF area 1.1 (0.3–1.7) 0.8 (0.6–2.3) 0.9 (0.3–1.4) 2.3 (0.8–3.3) 0.04

HAART: highly active antiretroviral therapy; SDNN: standard deviation of all NN intervals; pNN50: the proportion derived by a division of the number of pairs of adjacent NN intervals differing by more than 50 ms in the entire recording by the total number of all NN intervals; r-MSSD, the square root of the mean of sum of the squares of differences between adjacent NN intervals; LF: low frequency; HF: high frequency. values for differences among the four categories applying F-test for continuous variables and or Chi-square for categorical variables. *Median (interquartile interval); diabetics ≠ controls, ; diabetics ≠ controls, ; naïve ≠ controls, ; diabetics ≠ controls, ; naïve ≠ controls, ; diabetics ≠ controls, ; naïve ≠ controls, ; diabetics ≠ controls, .