Research Article

Mathematical Analysis of a General Two-Patch Model of Tuberculosis Disease with Lost Sight Individuals

Table 1

Numerical values for the parameters of the model.

ParametersDescriptionEstimated value/rangeReference

Recruitment rate into the class100/yrAssumed
Recruitment rate into the class110/yrAssumed
Transmission coefficient in patch 1VariableAssumed
Transmission coefficient in patch 2VariableAssumed
Per capita death rate in patch 10.019896/yrEstimated
Per capita death rate in patch 20.019897/yrEstimated
Progression rate from to next class in patch 10.00013/yrAssumed
Progression rate from to next class in patch 20.00023/yrAssumed
Effective chemoprophylaxis in the class0/yrEstimated
Effective chemoprophylaxis in the class0/yrEstimated
Lost sight individuals still able to transmit disease in patch 10.46/yrEstimated
Lost sight individuals still able to transmit disease in patch 20.48/yrEstimated
Effective therapy in class0.8182/yrEstimated
Effective therapy in class0.8183/yrAssumed
Return rate in care centre for patch 10.23/yrEstimated
Return rate in care centre for patch 20.23/yrEstimated
Infectious individuals in care centre of patch 1 who can stay in care centre0.59/yrEstimated
Infectious individuals in care centre of patch 2 who can stay in care centre0.5903/yrEstimated
Infectious individuals in care centre of patch 1 who disappear0.019/yrEstimated
Infectious individuals in care centre of patch 1 who disappear0.01905/yrEstimated
Migration rate of susceptible individuals from patch 1 to patch 20.07/yrAssumed
Migration rate of susceptible individuals from patch 2 to patch 10.0701/yrAssumed
Migration rate from latent class to latent class 0.05/yrAssumed
Migration rate from latent class to latent class 0.0503/yrAssumed
Migration rate of infectious individuals from patch 1 to patch 20.02/yrAssumed
Migration rate of infectious individuals from patch 2 to patch 10.0201/yrAssumed
Additional death rate in 0.0575/yrAssumed
Additional death rate in 0.05751/yrAssumed
Additional death rate in 0.0565/yrAssumed
Additional death rate in 0.05651/yrAssumed
Fast progression to the class0.015/yrAssumed
Fast progression to the class0.016Assumed