From Experimental Approaches to Computational Techniques: A Review on the Prediction of Protein-Protein Interactions
Figure 1
A graphical depiction PPI predictive tasks. (a) Direct binary interacting between two proteins; (b) proteins interact directly or interact indirectly through functional associations; and (c) Pathways represent logically linked connections for instance signal transduction. The nodes represent proteins; solid lines between the nodes represent direct interactions while dashed lines represent indirect functional associations.
(a) Direct PPI
(b) Direct PPI and indirect functional associations
