From Experimental Approaches to Computational Techniques: A Review on the Prediction of Protein-Protein Interactions

Table 3

A list of popular databases containing PPI information for organisms.

Database	Data Type	Organisms	URL	Reference
BioGRID	Experimental and manually curated data	22 organisms including: yeast, fruit fly, worm, human	http://bind.ca	[68]
Database of Interacting Proteins (DIP)	Experimental and structural data	274 organisms including: yeast, human, rat, mouse, fly and worm	http://dip.doe-mbi.ucla.edu/	[15]
Munich Database of Interacting Proteins (MIPS)	Experimental, functional predictions and manually curated	Mouse, human, yeast	http://www.helmholtz-muenchen.de/en/ibis	[25]
Saccharomyces genome database (SGD)	Experimental and manually curated	Yeast	http://www.yeastgenome.org/
IntACT	Experimental and manually curated	Includes the organisms: yeast, human, rat, mouse, fly and worm	http://www.ebi.ac.uk/intact/site/	[69]
Human Protein Reference Database	Experimental and manually curated	Human	http://www.hprd.org/
MINT	Experimental and manually curated	30 organisms including: yeast, human, rat, mouse, fly and worm	http://mint.bio.uniroma2.it/mint/	[70]