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Advances in Artificial Intelligence
Volume 2012 (2012), Article ID 457351, 7 pages
http://dx.doi.org/10.1155/2012/457351
Research Article

A Cultural Algorithm for the Representation of Mitochondrial Population

Department of Informatics, Ionian University, Plateia Tsirigoti 7, 49100 Corfu, Greece

Received 31 May 2012; Accepted 14 August 2012

Academic Editor: Catalina Cocianu

Copyright © 2012 Athanasios Alexiou and Panayiotis Vlamos. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We propose a novel Cultural Algorithm for the representation of mitochondrial population in mammalian cells as an autonomous culture. While mitochondrial dysfunctions are highly associated with neurodegenerative diseases and related disorders, an alternative theoretical framework is described for the representation of mitochondrial dynamics. A new perspective of bioinspired algorithm is produced, combining the particle-based Brownian dynamics simulation and the combinatorial representation of mitochondrial population in the lattice, involving the optimization problem of ATP production in mammalian cells.