Efficacious End User Measures—Part 1: Relative Class Size and End User Problem Domains

Table 9

The top two JPTs have been “tuned” to a population where the diseased population is one hundredth of the undiseased population. In this environment, the two tests appear statistically indistinguishable.

(a)

Actual RA condition
		Diseased	Not diseased
Anti-CCP	Positive	0.67	5
test result	Negative	0.33	95
	Totals	1	100
EPA	144 (136–150)

(b)

Actual RA condition
		Diseased	Not diseased
RF test	Positive	0.69	15
Result	Negative	0.31	85
	Totals	1	100
EPA	137 (131–143)