Review Article
Advances in Stem Cell Therapy for Erectile Dysfunction
Table 4
Published studies of stem cell therapy for cavernous nerve injury erectile dysfunction.
| Publication year | First author | CN injury method# | Stem cell type | Modification/supplementation* | Transplantation route | Reference |
| 2004 | Bochinski | Crush | Allogeneic ESC | BDNF transduction | IC or intra-MPG | [94] | 2006 | Kim | Transection | Allogeneic SkMSC | None | IC | [95] | 2009 | Fall | 5-mm resection | Allogeneic BMMNC | None | IC | [96] | 2010 | Albersen | Crush | Autologous ADSC | None | IC | [97] | 2010 | Kendirci | Crush | Allogeneic BMSC | p75LNGFR selection | IC | [98] | 2011 | Lin | 5-mm resection | Autologous ADSC | None | Nerve graft | [99] | 2011 | Woo | Transection | Allogeneic SkMSC | None | IC | [100] | 2012 | Fandel | Crush | Autologous ADSC | None | IC | [101] | 2012 | Kim | Crush | Allogeneic BMSC | BDNF transduction | Intra-MPG | [102] | 2012 | Kovanecz | 5-mm resection | Mouse SkMSC | Oral sildenafil | IC | [103] | 2012 | Piao | Crush | Human ADSC | BDNF PLGA | CN scaffold | [104] | 2012 | Qiu | Radiation | Allogeneic ADSC | None | IV | [105] | 2012 | Qiu | Crush | Autologous SVF | None | IC | [106] | 2013 | Jeong | Crush | Human ADSC | BDNF PLGA | CN scaffold |
[107] | Oral udenafil | 2013 | Kim | Crush | Human ADSC | NGF hydrogel | CN scaffold | [108] | 2013 | You | Not described | Human BMSC | None | IC + Periprostatic | [109] | 2013 | You | Stretch | Human ADSC | None | IC + Periprostatic | [110] | 2013 | Choi | Crush | Human testis SC | None | Periprostatic | [111] | 2013 | Ying | Crush | Autologous ADSC | None | IC | [112] |
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For enhancing stem cell’s therapeutic efficacy.
#All performed in rats.
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