(a) Tumor patient MRI brain image

(b) SPM t-test map

(c) HMM LLR map

Figure 5: Tumor patient high-resolution image and glass maps for SPM test and 2-state HMM likelihood ratio test. The patient has a tumor on his left frontal lobe from (a). No supplemental voxels from SPM t-test (b). “D” and “F” are supplemental voxels detected from HMM LLR map in (c).