The Biosynthesis of the Molybdenum Cofactor in Escherichia coli and Its Connection to FeS Cluster Assembly and the Thiolation of tRNA

Figure 3

Organization of the genes involved in the biosynthesis of Moco in E. coli. In total, 11 genes are involved in the biosynthesis of Moco in E. coli. These are organized into 5 different gene loci termed moa, mob, moc, moe, and mog. Genes of known function are colored in white. Black dots indicate promotor regions. The genes are drawn approximately to scale. Additional operons with a role for in Moco biosynthesis, such as the isc operon or the mod operon for molybdate transport, are not shown.