Inferring Biological Mechanisms by Data-Based Mathematical Modelling: Compartment-Specific Gene Activation during Sporulation in Bacillus subtilis as a Test Case
Figure 1
The regulation of the transcription factors during sporulation in Bacillus subtilis. (a) Differential cell fate during sporulation in B. subtilis: in response to starvation, B. subtilis divides asymmetrically and becomes active in the smaller compartment. (b) The regulatory networks that controls . (c) A contact map of the regulatory network. All possible interactions between regulatory components are indicated. Boxes represent complexes. Circles represent binding sites, and connecting lines indicate binding interactions. Circles that are both black and white demonstrate binding sites for competing ligands. (a) and (b) have been reproduced from [47].
