Cotranslational Protein Folding and Terminus Hydrophobicity

Figure 6

Difference between cotranslational and in vitro success rate against difference in terminus hydrophobicity (N−C) for HP lattice models. The blue lines (squares and dashes) are for all 24,900 sequences of length 20; the dashed line is for “trimmed” sequences, where the first and last four residues of each sequence are removed. The red lines (circles and dots) are for all 52,183 sequences of length 21; the red dotted line is for trimmed 21-mer sequences. Note that the positive relationship continues for 21-mers, but that it is largely lost when trimming occurs.