Computational Design of a DNA- and Fc-Binding Fusion Protein

<table>1LP1: sequence of the Z domain. 1MDY: part of the sequence of MyoD. Red marked amino acids are used as part of the seed sequence. Seed: seed sequence for the optimization. The blue and magenta marked amino acids are fixed during optimization. The initial population was created by randomly mutating black marked amino acids. JW70: selected model of the optimization aligned to the seed sequence.</table>

Advances in Bioinformatics

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Figure 2

Figure 2: Computational Design of a DNA- and Fc-Binding Fusion Protein 