457578.fig.004a
(a)
457578.fig.004b
(b)
Figure 4: (a): JW70 after 20 ns MD simulation (blue) aligned to the structure of the Z domain from 1LP1 after 10 ns MD simulation (orange). (b): model of the seed sequence after 20 ns MD simulation (purple) aligned to the Z domain from 1LP1 (orange). Helix 3, which contains the new DNA-binding site, is shown on top.